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Long-Read Sequencing Uncovers Congenital Adrenal Hyperplasia in Newborns
5+ hour, 56+ min ago (888+ words) In a groundbreaking study, researchers have embarked on an unprecedented exploration of congenital adrenal hyperplasia (CAH) through the lens of advanced genomic technologies. This sophisticated investigation, led by a team including Liang, Zhu, and Liang, delves into a cohort comprising…...
Unveiling Sea Buckthorn’s Peroxidase Genes in Lignin Production
9+ hour, 46+ min ago (944+ words) A groundbreaking study has emerged highlighting the previously uncharted territory of the class III peroxidase gene family in sea buckthorn, a plant scientifically known as Hippophae rhamnoides subsp. sinensis Rousi. This extensive exploration, led by a team of dedicated researchers…...
Glucocorticoid Receptor Levels Link to Zebrafish Lateralization
12+ hour, 22+ min ago (917+ words) In a groundbreaking study, researchers have unveiled significant insights into the intricate relationship between glucocorticoid receptor expression and visual lateralization in zebrafish. This research, conducted by a team led by Rovegno, Frigato, Dalla Valle, and their colleagues, shines a spotlight…...
Comparing Aptamer and Antibody Protein Measures Across Ancestries
12+ hour, 38+ min ago (772+ words) In a groundbreaking study poised to redefine biomolecular measurement across diverse populations, researchers Nicholas, Katz, Tahir, and colleagues have unveiled a comprehensive cross-ancestry comparison of aptamer and antibody protein assays. Their work, soon to be published in Nature Communications in…...
Bird eyes have capabilities that should not be possible
18+ hour, 49+ min ago (729+ words) Bird eyes have puzzled scientists for centuries. One part of the mystery comes from a simple question. How can bird retinas stay alive without oxygen? A new study published in the journal Nature finally explains this strange ability. The research…...
Gene Editing Market Overview and Leading Players: Thermo Fisher Scientific, Merck, Horizo??n Discovery, Sangamo BioSciences, Integrated DNA Technologies, Lonza, New England Biolabs, OriGene Technologies
22+ hour, 21+ min ago (81+ words) Gene Editing Market Overview and Leading Players: Thermo Fisher'openPR.com Gene Editing Market Overview and Leading Players: Thermo Fisher Scientific, Merck, Horizo??n Discovery, Sangamo BioSciences, Integrated DNA Technologies, Lonza, New England Biolabs, OriGene Technologies Press release from: STATS N…...
Rewrite LetA defines a structurally distinct transporter family as a
1+ day, 11+ hour ago (354+ words) To assess whether LetA is evolutionarily related to known transporter families, we performed a structure-based search of the Protein Data Bank (PDB) using Foldseek37. We were unable to identify structural similarity to known transporter folds, suggesting that LetA represents a new…...
Rewrite Construction of complex and diverse DNA sequences using DNA
1+ day, 12+ hour ago (1418+ words) Sidewinder can also assemble defined diversities across a large number of positions along the entire length of a DNA sequence to construct combinatorial libraries. In a combinatorial library, each variable position is diversified and assembled into a synthetic sequence with…...
Rewrite Four camera-type eyes in the earliest vertebrates from the Cambrian
1+ day, 13+ hour ago (85+ words) Vertebrate vision is mainly accommodated by a pair of lateral image-forming camera-type eyes and is supplemented in non-mammalian vertebrates by a dorsal pineal complex (pineal and parapineal organs) functioning as photoreceptive and/or endocrine organs1. The pineal complex shares a common…...
Rewrite Identification of an allosteric site on the E3 ligase adapter
1+ day, 14+ hour ago (301+ words) Cereblon (CRBN) is the target of thalidomide derivatives1 that achieve therapeutic efficacy against some haematologic neoplasias2,3,4 by recruiting neosubstrates for degradation5,6,7. Despite the intense investigation of orthosteric thalidomide derivatives, little is known about alternate binding sites on CRBN. Here we report an evolutionarily…...