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3+ hour, 46+ min ago   (391+ words) The study, published in Nature, uses base editing (see BioNews 848, 924, 1035 and 1285) to investigate the role of the gene NANOG in the earliest stages of human development. Named after Tír na nÓg, the mythical Celtic 'Land of the Young', NANOG was…...

3+ hour, 46+ min ago   (352+ words) In our recent study published in Nature, my colleagues and I make use of novel genome editing techniques to better understand human embryology (see BioNews 1345 and 1349). There has already been speculation about the future applications of this work, but any…...

6+ hour, 35+ min ago   (271+ words) The Indo-Japan venture aims to support IVF laboratories and fertility centres in improving the accuracy, reliability, and consistency of genomic testing, contributing to the continued evolution of India's assisted reproduction ecosystem DSS Takara Bio India is strengthening support for reproductive…...

11+ hour, 22+ min ago   (14+ words) Moomoo...

1+ hour, 16+ min ago   (421+ words) Chlamydomonas chlororibosome architecture mapped by cryo-ET and purified ribosome cryo-EM A new report in Nature Plants combines in situ cryo-electron tomography with high-resolution single-particle cryo-EM to reveal how chloroplast ribosomes in Chlamydomonas reinhardtii are reshaped by a small-subunit extension encoded…...

1+ hour, 16+ min ago   (358+ words) Researchers have uncovered a timing system that helps the Drosophila nervous system generate many neuron types from shared progenitors. The study focuses on how sequential “birth order” is translated into distinct cell fates, a principle long suspected in insects and…...

4+ hour, 3+ min ago   (358+ words) Insect wings are packed with sensory equipment, but the question of whether moths could truly “smell” with their wings has remained largely open. New work from Sonja Bisch-Knaden and Bill Hansson at the Max Planck Institute for Chemical Ecology now…...

4+ hour, 39+ min ago   (304+ words) Cells communicate and advertise their identity using extracellular vesicles—microscopic cargo carriers released into bodily fluids. Detecting vesicle signatures from specific cell types, especially cancer, has been a central challenge for liquid biopsies because target particles are scarce and often…...

5+ hour, 27+ min ago   (437+ words) AI-designed protein redesigns are shown to reshape the rules of evolution in a new Nature study, offering a “boosted starting point” for rapidly finding high-function enzyme variants....

7+ hour, 8+ min ago   (207+ words) Next, researchers prepare cellular lysates for analysis. The workflow then diverges into two readouts. In one route, the lysates undergo click chemistry with a fluorophore, allowing lipid–protein conjugates to be visualized directly using in-gel fluorescence. This provides a rapid…...