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A computational investigation prioritizes high-risk nonsynonymous mutations in SLC22A transporter genes that may alter protein stability and metformin pharmacokinetics in polycystic ovary syndrome.
Ancient DNA is uncovering forgotten migrations that may have shaped the origins of English, German, and Celtic languages, challenging what researchers thought they knew about Europe’s linguistic history. How can researchers trace…
Children & Teens: 646-895-6193 Available 24 hours a day, 7 days a week Memorial Sloan Kettering Cancer Center was founded in 1884, and today is a world leader in patient care, research, and educational programs. By Matthew…
While the data comes from non-neuronal cell lines, the authors think that the successive accumulation of fatigued, and thus dysregulated, stretches of chromatin could play a role in aging and neurodegeneration. They also implied…
A retrospective study identifies distinct gut microbiome signatures in C. difficile-positive and negative antibiotic-associated diarrhea, revealing unique taxonomic profiles despite similar reductions in overall diversity.
Children & Teens: 646-895-6193 Available 24 hours a day, 7 days a week Memorial Sloan Kettering Cancer Center was founded in 1884, and today is a world leader in patient care, research, and educational programs. By Matthew…
Wine sediment as an AI memory metaphor What racking wine teaches about agent memory The mead's lees on October 21, with the racking cane at the edge. Everything the siphon left behind stays here. That layer at the bottom of my mead fermenter did most of the work of turning…
Of the three isoforms of phospholipase A2 (PLA2) found in the mammalian brain—group II, IVA and VIA—the researchers focused on the group IVA isoform (GIVA-PLA2) because the GII-PLA2 is absent from the J20 line due to an inbred…
Manuela Fuchs, University of Otago; Leah Smith, University of Otago, and Natalie Kyte, University of Tübingen With their spindly legs and geometric heads, they look more like miniature spacecraft than anything living on Earth. But bacteriophages, or simply phages, are among the most abundant biological entities on the planet. These…