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Latest Articles
Scientists Created Females and Restarted Sexual Reproduction using a Single Male Mouse
3+ hour, 38+ min ago (596+ words) They created fertile female mice from cells carrying the male genome. How many parents does it take to make a family? According to a new study, just one. In a striking experiment, researchers in Japan used cells from male mice…...
EasyGrid Simplifies Cryo-Electron Microscopy Sample Preparation | Microbiology
6+ hour, 11+ min ago (421+ words) EasyGrid Simplifies Cryo-Electron Microscopy Sample Preparation Labroots EasyGrid Simplifies Cryo-Electron Microscopy Sample Preparation A new method published in Nature Methods removes much of the guesswork and time-consuming optimization from sample preparation for cryo-electron microscopy and tomography (cryo-EM/ET). To image…...
How Plant-Specific and Conserved PAF1 Complex Mechanisms Respond to
2+ hour, 44+ min ago (609+ words) A new study in Arabidopsis thaliana has identified the polymerase-associated factor 1 complex, or PAF1C, as a central component of the plant response to DNA replication stress. The findings reveal that PAF1C does more than support transcription: it also helps protect replication forks…...
NJU-PKU Team Achieves High-Fidelity Lensless Imaging of Dynamic Scenes in
4+ hour, 57+ min ago (562+ words) Lensless cameras may soon become far more capable of recording moving biological samples, thanks to a new computational imaging framework developed by researchers at Nanjing University and Peking University in China....
Whole-Body Proteome Atlas Reveals 41 Potential Cancer Drug Targets
12+ hour, 7+ min ago (575+ words) If the human genome is a static blueprint of life, the human proteome acts as a real-time GPS, tracking how cells move, mature, and malfunction. Scientists at Westlake University built a whole-body navigation system by mapping protein distributions across healthy,…...
Scientists uncover tRNA changes driving Chagas parasite transformation
2+ day, 18+ hour ago (308+ words) The researchers used tRNA sequencing, mass spectrometry, and bioinformatics analyses to map the chemical alterations present in these molecules and to investigate their role. Then, they used the CRISPR gene-editing tool to evaluate the impact of the absence of one…...
Designing Better Biomedical Hydrogels Through Molecular Building Blocks and
2+ day, 16+ hour ago (561+ words) A new review suggests that the next generation of biomedical hydrogels could be designed less like uniform gels and more like precisely engineered miniature landscapes, with organized structures that control how forces, water, ions, drugs and biological signals move through…...
AI Helps Researchers Decode DNA Sequence Crucial for Gene Activation
2+ day, 17+ hour ago (614+ words) The molecular switch that helps determine whether a human gene is turned on or remains silent has been decoded with the help of artificial intelligence....
Single-cell study reveals sex-specific nonlinear trajectories of immune
2+ day, 17+ hour ago (614+ words) A new study published in Nature Communications is drawing attention to an increasingly important question in immunology: does the immune system age in the same way in women and men? The research, led by H. Park, N. Le Bert and A. Bertoletti, examines…...
New method reveals how degenerative diseases affect individual cells
2+ day, 19+ hour ago (574+ words) Scientists at the University of Cologne, University Hospital Cologne, and the Max Planck Institute for Metabolism Research have developed a computational method that can measure cellular damage with unprecedented precision....