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Mapping Protein Energy Landscapes at Scale
1+ hour, 40+ min ago (908+ words) In a groundbreaking advance in protein biophysics, researchers have unveiled detailed insights into the energy landscapes of proteins, challenging long-standing assumptions about protein stability and cooperativity. By harnessing site-resolved hydrogen-deuterium exchange (HDX) nuclear magnetic resonance (NMR) and innovative protein design…...
Revealing the Hidden Microproteins of the Dark Proteome | Cell And Molecular Biology
9+ hour, 44+ min ago (226+ words) Proteins typically have a three-dimensional structure and are made up of strings of amino acids. But an amino acid string needs to only be a certain length, and have a likely biological role to be considered a protein. But it…...
Scientists working on "green" sunscreen using E. coli | Nation | iosconews. com
4+ hour, 57+ min ago (514+ words) E. coli could be used to produce a "green" sunscreen ingredient found in fish, suggests new research. Many marine creatures survive relentless sunlight in open water without getting burned by making their own natural sunscreen, say scientists. Now humans could be…...
Scientists working on "green" sunscreen using E. coli
4+ hour, 57+ min ago (514+ words) E. coli could be used to produce a "green" sunscreen ingredient found in fish, suggests new research. Many marine creatures survive relentless sunlight in open water without getting burned by making their own natural sunscreen, say scientists. Now humans could be…...
Mouth Stem Cells Show Promise in Overcoming Brain Cancer Defenses
12+ hour, 48+ min ago (1010+ words) Researchers at the University of Reading have uncovered a compelling new approach to combat glioblastoma, the most aggressive and lethal form of brain cancer in adults. Their groundbreaking work focuses on the unique properties of stem cells derived from the…...
Tracing 180 Years of "Plant Destroyer" Research: A Journey Through
13+ hour, 13+ min ago (919+ words) Nearly two centuries ago, a microscopic organism unleashed a catastrophic famine that reshaped human history and agriculture alike. This destructive agent, Phytophthora infestans, the notorious culprit behind the Irish Potato Famine, continues to intrigue scientists with its complex biology and…...
Cook Inlet belugas [IMAGE] | Eurek Alert! Science News Releases
14+ hour, 18+ min ago (37+ words) Cook Inlet belugas (IMAGE) Eurek Alert! Cook Inlet belugas swimming in northern Cook Inlet, near Anchorage, Alaska. Credit must be given to the creator. More on this News Release UW researchers decipher beluga calls to bolster conservation efforts...
MICU Proteins Drive Calcium-Based Mitochondrial Energy Control
16+ hour, 30+ min ago (719+ words) In a groundbreaking study set to reshape our understanding of mitochondrial regulation, researchers have unveiled an unexpected mechanism by which cellular energetics are controlled. The prevalent dogma that mitochondrial matrix calcium concentration ([Ca]) serves as the pivotal regulator of mitochondrial…...
AI Produces First Comprehensive Models of Proteins in Motion
20+ hour, 40+ min ago (198+ words) Looking ahead, the research group intends to enhance LD-FPG's capacity to model larger proteins and multimeric complexes, extending its applicability across a broad spectrum of biological macromolecules. Further refinements aim to boost computational efficiency and fidelity, striving for even closer…...
Glycocalyx Exchange Powers Liquid Biopsies of Endothelium
1+ day, 1+ hour ago (794+ words) A groundbreaking study has unveiled a novel mechanism by which endothelial function'a critical determinant of vascular health'can be monitored through a surprisingly accessible medium: the interaction between the endothelial glycocalyx and erythrocytes. This scientific advancement offers a revolutionary avenue for…...