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1+ hour, 6+ min ago   (312+ words) Duke University School of Medicine researchers have unveiled Raygun, an artificial intelligence framework that can redesign proteins at a scale reminiscent of natural evolution. Unlike conventional protein engineering, which often starts from scratch or makes limited changes, Raygun can generate…...

3+ hour, 49+ min ago   (236+ words) Mosaic chromosomal alterations are genomic abnormalities present in only a subset of cells. Though often subtle, they can accumulate with age and can influence immune function and disease risk. To understand why some clones persist while others fade, the researchers…...

11+ hour, 51+ min ago   (235+ words) ISAAA.org - Enhancing Soybean's Phytophthora sojae Resistance Through Gene Editing Northeast Agricultural University researchers reported in the journal Plants that overexpression of a soybean gene via CRISPR-Cas9 improves resistance to Phytophthora root rot, a major soybean disease that impacts yield…...

7+ hour, 54+ min ago   (290+ words) Models Bioengineer.org A new approach dubbed ProteinGuide aims to let researchers steer protein sequence generative models using auxiliary experimental or user-specified information—without the heavy burden of retraining the generative model itself In a field where model updates typically…...

11+ hour, 48+ min ago   (164+ words) The authors also describe changes in inflammatory and remodeling pathways, suggesting that adipose function is shaped by immune signaling and tissue repair dynamics. Such pathways may influence how readily brown-like thermogenic features emerge—or fail to emerge—under metabolic stress....

13+ hour, 15+ min ago   (420+ words) Tokyo, Japan—How much should an organism rely on memory when the present is good enough? New work from the Institute of Industrial Science, The University of Tokyo, and RIKEN reframes memory as an economic resource rather than a free…...

15+ hour, 44+ min ago   (275+ words) Researchers at the National Institute for Physiological Sciences report an unexpected role for smooth septate junction (sSJ) proteins in controlling growth-related signaling during intestinal differentiation. sSJ proteins, previously characterized as adhesion components, are shown to regulate the spatial dynamics of…...

1+ day, 5+ hour ago   (615+ words) [Purdue University] Sixty-six million years ago, an asteroid about the size of Mount Everest smacked into Earth near where the Yucatan Peninsula is today. That impact created the Chicxulub crater and may have knocked out about three-quarters of all living…...

1+ day, 1+ hour ago   (278+ words) Salt stress is rapidly eroding crop productivity worldwide, and medicinal plants are not spared. For Salvia miltiorrhiza, salinization threatens both survival and the biochemical machinery that produces tanshinones—high-value molecules used in traditional and modern therapeutics. Now, researchers report the…...

1+ day, 3+ hour ago   (203+ words) Tunneling nanotubes (TNTs) proved capable of carrying cellular components and organelles across separation distances reaching about 100 micrometers. This is a crucial scale because it allows exchange beyond what diffusion alone would readily accomplish within relevant timeframes. The nanotubes were not…...