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A team of researchers led by Cardiff University has developed a promising new gene-editing approach that could transform the treatment of Huntington's disease in the future. Huntington's disease is caused by repetitive "stutters" in DNA - specifically repeated CAG sequences - that…
AmplexDiagnostics and Scope Biosciences are proud to introduce a groundbreaking solution in molecular diagnostics. In a new approach, "eazySNP" combines the highly specialized molecular technologies LAMP and CRISPR. By integrating these two methods, eazySNP enables the rapid and highly specific…
A new era of genetic manipulation seems to be on the horizon. While humans have manipulated the genes of plants and animals for thousands of years through selective breeding, scientific advances in the last 50 years have given us the ability…
Guided by these metagenomic observations, the team isolated and screened microorganisms from rice rhizosphere soil enriched by the rotation. P-11 F emerged as a novel strain with activity against R. solani. The supplied study abstract does not report the number of isolates…
A structural study shows how Norrin, FZD4, TSPAN12 and LRP5 assemble, enabling engineered surrogate proteins with enhanced signaling potency.
A 2026 mini-review finds that antimicrobial-resistance predictions become more reliable when gene presence is combined with expression, dosage, genomic context and population information. Article Title: From genome to phenotype: advances, challenges and One Health perspectives in the genomic prediction of antimicrobial…
Nature Structural & Molecular Biology (2026) Cite this article The 3D cryo-EM density maps were deposited in the EM Data Bank under the accession numbers EMD-77288, EMD-72089, EMD-71846 and EMD-77325. Atomic coordinates for the atomic model were deposited to the Protein Data Bank…
A three-family study combined arrays, exome sequencing, karyotyping, quantitative PCR and Sanger sequencing to identify two large deletions and one frameshift in PAX6, including two variants that also removed WT1. Subject of Research: Genetic diagnosis of PAX6-related congenital aniridia and WAGR syndrome…
EurekAlert! The left agar plate shows a Pandoraea bacterial strain (P. norimbergensis deltapdnM) that only produces pandorachelin B. The strain on the right agar plate (P. norimbergensis WT) only produces pandorachelin A. Elena Herzog and Keishi Ishida, Leibniz Institute for Natural Product Research and…
Close examination of the preserved material documented sex-associated differences that are relevant to future identification. The mature male had nine large backward-pointing tubercles on the back, compared with three in the female. Its mouth floor carried seven transverse rows of…