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News
Scientists discover a hidden switch that shuts down inflammation
3+ hour, 52+ min ago (659+ words) Scientists have uncovered a natural braking system that helps the immune system switch off inflammation and prevent harmful immune cells from building up. Boosting this pathway in people reduced inflammation-related immune changes and sped up pain relief, pointing toward potential…...
Chromosomal Chaos in Tumors May Blind the Immune System, Genome Study Finds
26+ min ago (758+ words) Scientists in Japan have taken one of the most detailed looks yet at how large-scale genome disruption inside tumor cells may quietly rewire the immune landscape around them, and their findings could help explain why some cancers mount virtually no…...
AI Graph Tool scFormer Uncovers Rare Cell States Hidden in Single-Cell and
1+ hour, 52+ min ago (75+ words) Rare cells punch far above their weight in biology. Populations that make up less than one percent of a tissue can drive tumor progression, immune evasion, drug resistance, and relapse, while others mark the first steps of lineage commitment or…...
Cryo-EM Reveals How ATP Switches Off the Human NLRP6 Inflammasome
2+ hour, 6+ min ago (55+ words) The innate immune system is built on a paradox: the same molecular machinery that defends the body against infection can, when mishandled, turn that defense against the body itself. Few proteins embody this tension as vividly as NLRP6, a human pattern-recognition…...
Scientists Combine Genome and Gene Expression Data to Pinpoint Genes That
2+ hour, 42+ min ago (580+ words) Plant height may seem like a simple trait, but in soybean it sits at the heart of one of agriculture’s most consequential trade-offs. Tall plants can shade weeds and capture light, yet they topple in wind and rain, complicate harvest,…...
Immune Enzymes From Neutrophils Quietly Switch Off Fat Burning
2+ hour, 55+ min ago (634+ words) For years, immunologists have regarded neutrophils as short-lived first responders, cells that surge into infected or injured tissue, unleash a burst of antimicrobial chemicals, and then die within hours....
AI Uncovers Hidden Human Protein That Builds Bridges Between Cells
3+ hour, 59+ min ago (679+ words) For most of modern biology, the hunt for new human proteins has followed a familiar path: read the genetic sequence, predict where genes begin and end, and work outward from there. That strategy has served science remarkably well, delivering the…...
Heart cells can ‘remember’ stress and use it for protection during chemotherapy
8+ hour, 27+ min ago (1157+ words) Early stress in mitochondria before birth helped mouse hearts resist later chemotherapy damage by creating lasting protective changes. Chemotherapy can save lives, but some drugs can also put the heart under serious strain. Doxorubicin, a chemotherapy used against several cancers,…...
Smart nanoparticles reprogram tumor immune cells to boost cancer attack
17+ hour, 36+ min ago (48+ words) Targeted lipid nanoparticles deliver mRNA to tumor-associated macrophages, reprogramming the immune environment and strengthening anti-cancer T-cell activity in mice. Smart nanoparticles reprogram tumor immune cells to boost cancer attack Targeted lipid nanoparticles deliver mRNA to tumor-associated macrophages, reprogramming the immune…...
Nanoparticles Emerge as a Powerful New Weapon Against Cellular Aging
5+ hour, 12+ min ago (87+ words) Cellular senescence, one of the most closely studied hallmarks of aging, has long been a paradox in biology. On the one hand, it protects organisms by halting the division of damaged cells that might otherwise become cancerous. On the other,…...