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News
Prime Editing Gets a Size Upgrade: Researchers Insert Large DNA Fragments
8+ hour, 47+ min ago (653+ words) The gene-editing field has long faced a stubborn trade-off. Tools such as CRISPR-Cas9 excel at cutting DNA and at making small, targeted changes, but installing large pieces of genetic material into a genome at a precise location — without causing collateral…...
Deep-Learning Framework Crop-GPA 2.0 Cracks the Shared Genetic Code of Crop
1+ day, 3+ hour ago (858+ words) Every improvement in a crop, whether it is a heavier ear of wheat, a more disease-resistant rice plant, or a maize hybrid that endures drought, ultimately traces back to variation written into the genome....
Johns Hopkins researchers break neuroimaging time barrier to reveal new clues about brain disease
2+ day, 8+ hour ago (301+ words) This stylized image illustrates the trajectories of brain cancer cells that were acquired in vivo over a period of 72 hours using the CloudScope. These cell trajectories are represented as colored trails, which are superimposed on the corresponding vasculature, depicted in…...
AlphaGenome Atlas maps more than 9 billion possible DNA changes
2+ day, 12+ hour ago (883+ words) AlphaGenome Atlas predicts the effects of more than 9 billion possible DNA changes. Learn what AVI does—and why this is not a diagnostic tool. That distinction matters. The Atlas is a map of predictions about DNA function, not a catalog…...
WATCH: Cloned in the USA
2+ day, 14+ hour ago (1873+ words) Twenty-five years ago today the media tour I was on after finding the lab in rural West Virginia ended abruptly, writes Joe Lauria. 8pm EDT Tonite! By Joe Lauria Special to Consortium News Find the lab, was my assignment from The…...
New AI Model for DNA Learns from Evolution to Study the Human Genome - University of California, Berkeley
2+ day, 21+ hour ago (656+ words) UC Berkeley researchers have created a new genomic language model, called GPN-Star, that excels at spotting genetic variants that impact human health. More than two decades after scientists first sequenced the entire human genome — all 3 billion “letters,” or base pairs,…...
Advancing whole-genome sequencing with long-range data
2+ day, 19+ hour ago (162+ words) The system is able to unlock challenging genomic regions, structural variants, and phased variant calls across the human genome, resulting in an extensive, high-accuracy human genome made simple. The workflow delivers powerful genomic insights and only needs simple library preparation....
AI Identifies Disease-Relevant Genetic Variants
2+ day, 20+ hour ago (596+ words) More than two decades after scientists first sequenced the entire human genome — all 3 billion “letters,” or base pairs, of DNA code — the meaning of much of this code remains a mystery. Researchers at UC Berkeley have created a new genomic language…...
Exeter researcher pioneers AlphaGenome Atlas, identifying genetic regions that could link to disease
2+ day, 19+ hour ago (281+ words) University of Exeter News The University of Exeter has collaborated with Google DeepMind, becoming among the first researchers in the world to test a new platform which contain predictions for the effects of 9 billion genetic variants – every single letter change…...
Single-cell maps reveal how enhancers regulate their target genes
2+ day, 17+ hour ago (846+ words) Genomic dark matter has long been the paradox at the heart of human genetics....