4+ min ago   (744+ words) For decades, the central obstacle to testing therapies that slow human aging has been painfully simple: aging takes decades to measure. A drug that genuinely delays the biological processes of aging would need years, often a lifetime, of follow-up before…...

25+ min ago   (68+ words) Aging has become a product. Across North America and Europe, companies now sell direct-to-consumer epigenetic tests that estimate a customer’s biological age from DNA methylation patterns, often bundled with supplements and lifestyle programs marketed as capable of slowing or even…...

1+ day, 15+ hour ago   (487+ words) As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations. These mutations can give the cells a growth advantage, laying the foundation for developing serious health conditions. Now, scientists at…...

2+ day, 14+ min ago   (837+ words) For roughly two centuries, human life expectancy climbed steadily as medicine, sanitation, nutrition, and healthcare improved. More recent research, however, suggests that this long upward trend may now be leveling off in developed countries. If that is the case, the…...

2+ day, 17+ hour ago   (229+ words) University of Rochester researchers found that removing a protein associated with persistent inflammation caused mice to age faster, challenging expectations that blocking it could slow aging. The finding suggests the protein, known as cGAS, may have both harmful and protective…...

2+ day, 9+ hour ago   (134+ words) Researchers discovered a surprising role for a protein involved in persistent inflammation, which can contribute to cell damage and diseases of aging such as cancer. The protein, called cGAS, is a hot area of study, said Vera Gorbunova, PhD, the…...

2+ day, 14+ hour ago   (961+ words) The team calculated 16 widely used epigenetic clocks alongside 94 additional DNA methylation biomarkers to assess whether these tools respond consistently to interventions intended to influence aging biology. “The central finding is that epigenetic aging biomarkers are not all measuring the same…...

3+ day, 2+ hour ago   (56+ words) Bioengineer.org Subject of Research: The role of the CD44 receptor as a molecular hub linking extracellular matrix remodeling to inflammaging, autophagy decline, senescence, and tissue homeostasis in aging Article Title: From matrix to nucleus: CD44 as a central regulator of inflammaging,…...

3+ day, 21+ hour ago   (725+ words) The Clinical Trial Vanguard Proteomic Aging Clocks Just Changed What a Phase 2a Trial Has to Prove The Nature Biotechnology paper published this week on integrating proteomic aging clocks into a Phase 2a geroprotective trial is not a longevity science curiosity. It…...

4+ day, 4+ hour ago   (746+ words) Your morning coffee may be doing more than helping you wake up. Research from Queen Mary University of London suggests that caffeine can activate an ancient cellular energy system involved in growth, stress resistance, and DNA repair. Those processes are…...