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BIOENGINEER.ORG - Bioengineering

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BIOENGINEER.ORG
bioengineer.org > four-gene-signature-tied-to-young-age-predicts-breast-cancer-recurrence-risk

Four-Gene Signature Tied to Young Age Predicts Breast Cancer Recurrence

7+ hour, 23+ min ago   (69+ words) Why do young women with breast cancer so often fare worse than older patients, even when their tumors look similar under the microscope? A new study published in Cancer Reports offers a fresh molecular clue. By mining large public genomic…...

BIOENGINEER.ORG
bioengineer.org > sequence-transformer-learns-dna-mutation-patterns-to-subtype-breast-cancer

Sequence transformer learns DNA mutation patterns to subtype breast cancer

2+ day, 3+ hour ago   (734+ words) Every tumor tells a story in its DNA, but the mutations themselves are only half the tale. Scientists have long known that breast cancers can be sorted into clinically meaningful subtypes based on gene-expression patterns such as the widely used…...

BIOENGINEER.ORG
bioengineer.org > multi-modal-data-integration-uncovers-predictive-biomarkers-for-ovarian-cancer

Multi-modal data integration uncovers predictive biomarkers for ovarian

1+ week, 1+ day ago   (742+ words) Precision oncology has long promised a future in which each patient’s tumor is read like a molecular instruction manual, with treatments selected to match the specific genetic faults driving the disease. Yet the promise has repeatedly stumbled in clinical trials,…...

BIOENGINEER.ORG
bioengineer.org > stanford-study-shows-molecular-glue-converts-cancer-driver-into-built-in-kill-switch

Stanford study shows molecular glue converts cancer driver into built-in

3+ week, 1+ day ago   (593+ words) A two-headed experimental drug has eradicated aggressive human lymphoma tumors in mice by turning one of cancer’s most important growth-driving proteins against the malignant cells it normally supports. The compound, called TCIP3, was developed by researchers at Stanford Medicine and works…...

BIOENGINEER.ORG
bioengineer.org > study-uncovers-overlooked-dna-mutation-pattern-linked-to-colorectal-cancer

Study uncovers overlooked DNA mutation pattern linked to colorectal cancer

3+ week, 3+ day ago   (618+ words) Researchers at the University of California San Diego and collaborating institutions have identified and validated a previously overlooked pattern of DNA mutations in colorectal cancer, revealing a recurring genomic feature that may reflect changes in the way tumor cells replicate…...