15+ min ago   (618+ words) Every day, computational biologists release new methods for analyzing genomes, single cells, microbiomes and molecular signatures, and every day researchers struggle with the same question: which method actually works best for their data? The answer usually depends on benchmarks—structured…...

5+ hour, 43+ min ago   (680+ words) Natural killer cells have long been celebrated as the swift, unsung assassins of the immune system, capable of detecting and destroying tumor cells without the elaborate priming that T cells require....

5+ hour, 43+ min ago   (674+ words) Spatial omics technologies have transformed biology by allowing scientists to measure gene expression, proteins, chromatin states and even metabolites directly within intact tissue sections, preserving the geographical context that single-cell methods discard....

20+ hour, 37+ min ago   (879+ words) Scientists have unveiled a new computational framework that brings together two of the most powerful technologies in modern biology—single-cell RNA sequencing and spatial transcriptomics—to reconstruct how populations of cells redistribute and change state across time within living tissues....

3+ day, 21+ hour ago   (699+ words) In a striking reminder of how much can hide inside two neighboring letters of the genetic code, researchers in Iran have identified a rare complex mutation in the TTPA gene that causes ataxia with vitamin E deficiency, a treatable but…...

5+ day, 9+ hour ago   (855+ words) A landmark international study has delivered the most comprehensive picture to date of the genetic architecture of multiple sclerosis, combining genome-wide association data from individuals across multiple ancestries with cutting-edge multiomics analyses to reveal where, and in which cell types,…...

5+ day, 10+ hour ago   (83+ words) In a discovery that is reshaping how scientists think about the biology of human reproduction, researchers have unveiled the molecular architecture and three-dimensional spatial organization of proteasomes inside the nucleus of human sperm cells. The findings, published in Nature Structural…...

5+ day, 22+ hour ago   (78+ words) Every process that keeps a plant alive—from the immune responses that fend off pathogens to the signaling cascades that help roots find water—depends on proteins physically touching one another. These countless molecular handshakes, collectively known as the protein…...