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Leveraging microbial phylogeny for computational efficiency - Nature Reviews Microbiology
5+ day, 2+ hour ago (128+ words) This Genome Watch article explores how taking into account known phylogenetic relationships can improve computational efficiency for genomics, enabling improved genome data compression and faster sequence search as datasets continue to expand. B'inda, K. et al. Efficient and robust search of…...
Mapping cis-regulatory mutations at scale in sorghum enables modulation of gene expression - Nature Biotechnology
1+ week, 1+ day ago (1583+ words) This necessary promoter region is flanked by two stretches enriched for hypermorphic deletions. These hypermorphic regions differ in their deletion size response; on average, large deletions (100250bp) in the region "400 to "200 from the transcription start site (TSS) activate transcription but smaller…...
In the trap of Arthrobotrys - Nature Microbiology
1+ week, 16+ hour ago (129+ words) Yen-Ping Hsueh used to think she was studying a fungus that traps nematodes. Fifteen years later, she realized she was the one who had been captivated, not by adhesive hyphae but by the irresistible mystery and quiet beauty of Arthrobotrys…...
Cell biology’s fantastic voyage to Planet Earth - Nature Methods
1+ week, 23+ hour ago (107+ words) Nature Methods (2026)Cite this article A nascent group of researchers sees planetary health as an urgent reason to bridge the molecular and planetary scales. This is shaping their strategies, methods, collaborations and outlook about their fields. Chen, K. et al. BBA…...
Candida albicans steals magnesium and Pseudomonas aeruginosa unleashes resistance - Nature Reviews Microbiology
1+ week, 2+ day ago (455+ words) Candida albicans steals magnesium and Pseudomonas aeruginosa unleashes resistance'Nature Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date…...
Rapid production of precisely edited cattle and mice via a single AAV delivered miniature IscB#/ωRNA# - Cell Discovery
2+ week, 3+ day ago (255+ words) Jinek, M. et al. Science 337, 816821 (2012). Yoon, Y. et al. Nat. Commun. 9, 412 (2018). Altae-Tran, H. et al. Science 374, 5765 (2021). Wang, M. et al. Cell Discov. 10, 31 (2024). Hirano, S. et al. Nature 610, 575581 (2022). Mizuno, N. et al. iScience 9, 286297 (2018). Zhang, J. et al. Genome Biol. 18, 35 (2017). Certo, M. et al. Nat. Methods 8, 671676 (2011). Littlejohn, M. et al. Nat....
Overcoming cytoskeleton instability in the early embryo - Nature Reviews Molecular Cell Biology
4+ week, 1+ day ago (336+ words) Overcoming cytoskeleton instability in the early embryo'Nature Your privacy, your choice We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media, as well as…...
Charting the 3D regulatory landscape of sex determination with geostatistics - Nature Structural & Molecular Biology
4+ week, 1+ day ago (282+ words) Nature Structural & Molecular Biology (2026)Cite this article METALoci, a computational framework to study the 3D genome, reveals a prominent rewiring of regulatory interactions during sex determination. This geostatistics-inspired method also uncovered a previously unknown non-coding regulatory region at the Fgf9 locus and…...
Extending microsecond time-resolved cryo-electron microscopy with laser flash melting - Nature Reviews Molecular Cell Biology
1+ mon, 2+ week ago (118+ words) Nature Reviews Molecular Cell Biology (2026)Cite this article Straub, M. S. et al. Laser flash melting cryo-EM samples to overcome preferred orientation. Nat. Methods 22, 18801886 (2025) Institute of Chemical Sciences and Engineering ISIC, EPFL, Lausanne, Switzerland Correspondence to Constantin R. Kr'ger. A patent has been…...
Long-term feeder cell-free cat intestinal organoid cultures to study Toxoplasma gondii’s sexual development - Communications Biology
1+ mon, 2+ week ago (1702+ words) We use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media, as well as to allow video information to be shared for both marketing, analytics…...