2+ mon, 4+ week ago   (330+ words) In the new study, researchers used genome editing to switch off the gene responsible for producing dihydroflavonol 4-reductase, an enzyme involved in a critical step just before anthocyanins are formed in red lettuce. Once this gene was disabled, the plants…...

3+ mon, 1+ week ago   (380+ words) Of course, the cell is not powerless in the face of such lesions. It has an extensive catalog of cellular mechanisms that are set in motion following DNA damage. DNA damage response, or DDR for short, is the technical term…...

3+ mon, 2+ week ago   (705+ words) By reexamining 3D images used to map the connections between brain cells, researchers are uncovering new information about a small, elusive, and often overlooked cellular appendage. In a new series of work, researchers at HHMI's Janelia Research Campus, the Allen Institute,…...

3+ mon, 2+ week ago   (490+ words) A longstanding mystery in Parkinson's disease research has been why some individuals carrying pathogenic variants that increase their risk of PD go on to develop the disease, while others who also carry such variants do not. The prevailing theory has…...

6+ mon, 1+ week ago   (560+ words) Chemogenetics involves directing cell behavior with small external molecules, often medications or dietary compounds, that activate specially engineered switches inside targeted cells. Unlike conventional drugs that can affect many tissues throughout the body, this method is designed to work only…...

10+ mon, 1+ week ago   (395+ words) Scientists at the University of California San Diego School of Medicine have created a new method that combines artificial intelligence (AI) with cutting-edge molecular biology tools to uncover what determines whether a macrophage becomes inflammatory or restorative. Their research also…...

8+ mon, 3+ week ago   (606+ words) Around 130 million years ago, the ocean’s most dominant hunters held far more power than any marine predator alive today. Recent research from McGill University reveals that during the Cretaceous period, some sea creatures sat at the very top of an…...

10+ mon, 3+ week ago   (781+ words) The findings, published in Proceedings of the National Academy of Sciences on August 7, 2025, identify new microproteins that could potentially serve as drug targets to treat obesity and other metabolic disorders. The study also showcases the value of CRISPR screening in…...

11+ mon, 16+ hour ago   (642+ words) Nina Kumowski, MD, of the Department of Radiology and Center for Systems Biology at Massachusetts General Hospital, is the lead author and Matthias Nahrendorf, MD, PhD of the Department of Radiology and Center for Systems Biology at MGH, is the…...