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News
Lab Models Take Center Stage in the Race to Improve Cancer Immunotherapy
8+ min ago (583+ words) Cancer immunotherapy has transformed the treatment landscape for many patients with solid tumors, delivering durable responses in diseases that once resisted nearly every therapeutic approach....
Scientists Combine Genome and Gene Expression Data to Pinpoint Genes That
22+ min ago (580+ words) Plant height may seem like a simple trait, but in soybean it sits at the heart of one of agriculture’s most consequential trade-offs. Tall plants can shade weeds and capture light, yet they topple in wind and rain, complicate harvest,…...
Immune Enzymes From Neutrophils Quietly Switch Off Fat Burning
35+ min ago (634+ words) For years, immunologists have regarded neutrophils as short-lived first responders, cells that surge into infected or injured tissue, unleash a burst of antimicrobial chemicals, and then die within hours....
Chemotherapy’s Hidden Survivors: Lactylation Switch Reveals How
1+ hour, 12+ min ago (667+ words) Colorectal cancer remains one of the deadliest malignancies worldwide, and even the most aggressive chemotherapy regimens can fail in a frustratingly subtle way. Tumors often shrink in response to treatment, yet a small population of cells survives in a quiet,…...
Immune Side Effects May Signal Stronger Tumor Shrinkage and Longer Survival
1+ hour, 25+ min ago (628+ words) When patients with advanced gastric cancer receive immune checkpoint inhibitors, one of the most puzzling phenomena in modern oncology is the apparent paradox that side effects can be good news....
AI Uncovers Hidden Human Protein That Builds Bridges Between Cells
1+ hour, 38+ min ago (679+ words) For most of modern biology, the hunt for new human proteins has followed a familiar path: read the genetic sequence, predict where genes begin and end, and work outward from there. That strategy has served science remarkably well, delivering the…...
Nanoparticles Emerge as a Powerful New Weapon Against Cellular Aging
2+ hour, 52+ min ago (87+ words) Cellular senescence, one of the most closely studied hallmarks of aging, has long been a paradox in biology. On the one hand, it protects organisms by halting the division of damaged cells that might otherwise become cancerous. On the other,…...
Lipid Metabolism Emerges as a Central Driver of Drug Resistance in
3+ hour, 2+ min ago (71+ words) Aggressive non-Hodgkin lymphoma remains one of the most stubborn challenges in modern hematology. Even with a therapeutic arsenal that now includes rituximab-based immunochemotherapy, targeted kinase inhibitors, immune checkpoint blockade, and chimeric antigen receptor T-cell therapies, a substantial fraction of patients…...
New AI Framework SCIGMA Unifies Spatial Multiomics Data With Built-In
3+ hour, 2+ min ago (674+ words) Spatial omics technologies have transformed biology by allowing scientists to measure gene expression, proteins, chromatin states and even metabolites directly within intact tissue sections, preserving the geographical context that single-cell methods discard....
Hidden RNA Tag Drives Paclitaxel Resistance in Bladder Cancer, Study Finds
3+ hour, 15+ min ago (75+ words) Bladder urothelial carcinoma remains one of the most challenging malignancies in oncology, a disease whose treatment has been persistently undermined by its remarkable ability to shrug off chemotherapy. Now, a team of researchers in China has uncovered a molecular mechanism…...