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News
Gelatin Hydrogel Salbutamol Study Retracted Over Overlapping Microscopy
11+ hour, 56+ min ago (682+ words) A study that promised a new way to deliver the asthma drug salbutamol sulphate through gelatin-based swellable hydrogels has been struck from the scientific record....
Aptamer-Guided CRISPR-Cas9 Delivery Could Make Cancer Genome Editing
12+ hour, 6+ min ago (55+ words) Gene editing has long promised a revolution in cancer medicine, yet the promise has remained stubbornly out of reach for one deceptively simple reason: getting the CRISPR-Cas9 machinery into tumor cells, and only tumor cells, is extraordinarily difficult. A new…...
Medicinal Plant Polysaccharide Yields Silver-Decorated Carbon Dots for
19+ hour, 11+ min ago (55+ words) Researchers in China have transformed a polysaccharide extracted from the rhizomes of Polygonatum cyrtonema Hua, a plant long valued in traditional food and medicine, into a highly engineered carbon nanomaterial that can detect trace organic pollutants at concentrations as low…...
Charge-Switching Lipids Make Lipid Nanoparticles Safer for Gene Delivery
1+ day, 7+ hour ago (833+ words) Lipid nanoparticles have become one of the most celebrated delivery vehicles in modern medicine, propelling messenger RNA vaccines to the forefront of the global response to the COVID-19 pandemic and opening a credible path toward RNA therapeutics for cancer, genetic…...
Balloon Catheters Fail to Boost Tumor Targeting in Holmium-166
2+ day, 18+ hour ago (55+ words) For patients with inoperable liver tumors, transarterial radioembolization offers a way to deliver lethal radiation doses directly into the vascular supply of malignancies while sparing healthy tissue. The technique depends on millions of microscopic radioactive spheres being carried by arterial…...
Focused ultrasound activates cells and delivers nanomedicine to fight
4+ day, 10+ hour ago (768+ words) Cancer treatment has long been constrained by a deceptively simple problem: getting enough drug into a tumor without poisoning the rest of the body....
Quinoxalinone nanoparticles target endoplasmic reticulum for tumor
4+ day, 10+ hour ago (484+ words) A new class of engineered nanoparticles that home in on the endoplasmic reticulum of cancer cells and, when illuminated, devastate tumors from within has shown near-complete suppression of tumor growth in mouse models, according to a study published in Bioengineering…...
Tumor-endothelial 3D model reveals ccRCC vessel abnormalities and drug
4+ day, 20+ hour ago (115+ words) The kidneys are among the most richly vascularized organs in the human body, and when clear cell renal cell carcinoma takes hold there, it exploits that blood supply with extraordinary aggression. The tumors are visibly suffused with vessels, a hallmark…...
New multimodal graph approach classifies esophageal motility disorders
5+ day, 8+ hour ago (57+ words) Diagnosing disorders of the esophagus has always been as much art as science. When patients complain of dysphagia—the difficulty swallowing food, liquids, or even saliva—physicians turn to high-resolution impedance manometry, or HRIM, a procedure in which a thin…...
Glucosamine-coated carbon nanotubes show promise as antibacterial agents
5+ day, 14+ hour ago (862+ words) In the escalating arms race between medicine and multidrug-resistant bacteria, scientists have reported a strikingly simple-sounding but powerful advance: sugar-coated carbon nanotubes loaded with antibiotics that wipe out resistant strains almost completely while leaving human cells largely unharmed....