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News
Browser-Based TMA-Grid Tool Brings FAIR, Zero-Footprint De-Arraying to
1+ day, 8+ hour ago (559+ words) Tissue microarrays have quietly become one of the workhorses of modern cancer research, allowing hundreds of tissue cores from different patients to be packed onto a single microscope slide and scanned in one pass....
Real-World Study Shows Nefecon Cuts Proteinuria and Preserves Kidney
1+ day, 8+ hour ago (660+ words) A new real-world study offers some of the clearest practical evidence yet that Nefecon, the targeted-release formulation of the corticosteroid budesonide, can meaningfully reduce protein leakage and stabilize kidney function in patients with primary IgA nephropathy, including those who begin…...
BenchHub Turns Computational Biology Benchmarking Into a Living,
1+ day, 9+ hour ago (618+ words) Every day, computational biologists release new methods for analyzing genomes, single cells, microbiomes and molecular signatures, and every day researchers struggle with the same question: which method actually works best for their data? The answer usually depends on benchmarks—structured…...
Green Solvents and Microwaves Unlock Antioxidant Treasures Hidden in
1+ day, 10+ hour ago (55+ words) Chemists in Pakistan have shown that the secret to extracting powerful antioxidant compounds from the leaves of the lemon-scented eucalyptus tree lies in matching the polarity of the solvent to the chemistry of the target molecules. In a study published…...
Cryo-EM Reveals How ATP Switches Off the Human NLRP6 Inflammasome
1+ day, 11+ hour ago (55+ words) The innate immune system is built on a paradox: the same molecular machinery that defends the body against infection can, when mishandled, turn that defense against the body itself. Few proteins embody this tension as vividly as NLRP6, a human pattern-recognition…...
High-Flow Nasal Cannula Emerges as Lifeline for ALS Patients Who Cannot
1+ day, 11+ hour ago (703+ words) For people living with amyotrophic lateral sclerosis, the slow failure of the muscles that control breathing is the disease’s most feared complication. Non-invasive ventilation, delivered through a snugly fitted mask, has long been the standard of care, offering a documented…...
Photon-Counting CT Now Yields Density and Atomic Number Maps
1+ day, 12+ hour ago (540+ words) Computed tomography has long been one of medicine’s most powerful windows into the human body, but a fundamental limitation has always lurked beneath its grayscale images. Conventional CT measures how much X-rays are attenuated as they pass through tissue, a…...
New 14-Valent Pneumococcal Vaccine Shows Strong Safety and Immune Response
1+ day, 13+ hour ago (733+ words) Pneumococcal disease remains one of the most formidable vaccine-preventable threats to young children worldwide, and a newly reported phase IV trial from India offers encouraging evidence that a next-generation pneumococcal conjugate vaccine can meet the moment....
PROTACs Move From Lab Concept to Clinical Reality in Targeted Protein
1+ day, 13+ hour ago (746+ words) A sweeping new review published in Discover Chemistry charts the remarkable rise of proteolysis-targeting chimeras, better known as PROTACs, from a bold theoretical idea to one of the most closely watched platforms in modern drug discovery. Written by Sandip G....
Tea Catechins Transform Waste Rice Bran into Powerful Emulsion Stabilizers
1+ day, 13+ hour ago (55+ words) Rice bran, the fibrous outer layer stripped away when brown rice is polished into white rice, is produced at a staggering scale of more than 63 million tons every year. Most of it is pressed for its oil, but what remains…...