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News
New Sequencing Method Maps RNA Isoforms Across Brain Cells With Single-Cell
19+ min ago (529+ words) Every cell in the brain carries essentially the same genome, yet the same gene can produce a startling variety of RNA molecules. Through a process called alternative splicing, segments of a gene’s transcript can be included, skipped, or rearranged, generating…...
Seaweed-Derived Coating Matches Heparin at Keeping Blood From Clotting
1+ hour, 30+ min ago (628+ words) A coating built from red seaweed could soon replace one of medicine’s most indispensable yet most fragile ingredients....
Scientists Combine Genome and Gene Expression Data to Pinpoint Genes That
5+ hour, 52+ min ago (580+ words) Plant height may seem like a simple trait, but in soybean it sits at the heart of one of agriculture’s most consequential trade-offs. Tall plants can shade weeds and capture light, yet they topple in wind and rain, complicate harvest,…...
DartUniFrac Brings Megascale Computing to Microbiome Diversity Analysis
6+ hour, 55+ min ago (512+ words) Researchers have introduced DartUniFrac, a new software tool designed to carry out UniFrac-based microbiome comparisons at a scale that was previously impractical....
MemBrain v2 Brings End-to-End Membrane Analysis to Cryo-Electron Tomography
8+ hour, 7+ min ago (880+ words) Cryо-electron tomography has quietly become one of the most powerful windows into the interior of cells, allowing researchers to peer at the molecular machinery of life in a state close to its native, frozen-hydrated condition....
Scientists Discover CD55 Is the Hidden Switch That Powers Natural Killer
8+ hour, 33+ min ago (680+ words) Natural killer cells have long been celebrated as the swift, unsung assassins of the immune system, capable of detecting and destroying tumor cells without the elaborate priming that T cells require....
Protein Assembly, Not Abundance, Explains Why Cells Behave So Differently
9+ hour, 12+ min ago (689+ words) For decades, biologists have treated protein abundance as the closest available proxy for what a cell is actually doing. Measure how much of each protein a cell produces, the reasoning went, and you have a reasonable snapshot of its functional…...
Chemists Deploy Palladium to Switch Off and On a Key Amino Acid in Living
11+ hour, 43+ min ago (703+ words) Phenylalanine rarely gets top billing in discussions of molecular biology, yet this unassuming aromatic amino acid quietly underpins some of the most fundamental processes in the cell....
Dual-State Structures Reveal How Drugs Switch the Immune Receptor GPR84
13+ hour, 26+ min ago (69+ words) A receptor long viewed as one of the more enigmatic members of the lipid-sensing G protein-coupled receptor family is now coming into sharp molecular focus. New research published in Experimental & Molecular Medicine describes how structural snapshots of GPR84, captured in distinct…...
Cryo-EM Captures Hidden Pre-Active State That Switches On the Brain’s
14+ hour, 46+ min ago (663+ words) For decades, neuroscientists have marveled at the sheer speed of communication in the brain, and much of that speed depends on a single family of proteins known as AMPA receptors....