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News
Chemotherapy Speeds One Aging Marker in Breast Cancer but Leaves Epigenetic
8+ hour, 36+ min ago (520+ words) A new study is challenging one of the most common assumptions in the fast-growing field of biological aging research: that the different blood tests used to measure how fast a person is aging are, at some level, measuring the same…...
Engineered E. coli swarms record chemical and light inputs in visible
8+ hour, 46+ min ago (521+ words) Bacteria are famous for forming patterns, from the concentric rings of Proteus colonies to the branching networks that motile microbes paint across agar plates. Now researchers at Columbia University have turned one of biology’s most familiar workhorses, Escherichia coli, into…...
New Sequencing Method Maps RNA Isoforms Across Brain Cells With Single-Cell
9+ hour, 22+ min ago (529+ words) Every cell in the brain carries essentially the same genome, yet the same gene can produce a startling variety of RNA molecules. Through a process called alternative splicing, segments of a gene’s transcript can be included, skipped, or rearranged, generating…...
Proteomic Aging Clocks Enter the Clinic in Landmark Phase 2a Geroprotection
13+ hour, 12+ min ago (744+ words) For decades, the central obstacle to testing therapies that slow human aging has been painfully simple: aging takes decades to measure. A drug that genuinely delays the biological processes of aging would need years, often a lifetime, of follow-up before…...
Transposable Elements Drive the Birth of Vast Satellite DNA Repertoires in
13+ hour, 33+ min ago (597+ words) The genomes of true frogs have long puzzled geneticists. Amphibians are famous for carrying some of the largest and most repetitive genomes among vertebrates, and yet the detailed architecture of their repetitive DNA has remained poorly explored compared with mammals,…...
Hidden Cyanobacteria That Harvest Far-Red Light Revealed in Taiwan’s Hot
13+ hour, 54+ min ago (537+ words) Deep in the steaming runoff channels of Taiwan’s hot springs, a group of microbes has been quietly rewriting the rules of photosynthesis. These are the far-red light-utilizing cyanobacteria, or FRLCyano, organisms capable of extending oxygenic photosynthesis beyond the visible spectrum…...
AI Graph Tool scFormer Uncovers Rare Cell States Hidden in Single-Cell and
14+ hour, 5+ min ago (75+ words) Rare cells punch far above their weight in biology. Populations that make up less than one percent of a tissue can drive tumor progression, immune evasion, drug resistance, and relapse, while others mark the first steps of lineage commitment or…...
Machine Learning Meets X-Rays to Reveal the Hidden Architecture of Pea
14+ hour, 19+ min ago (95+ words) Every seed is a masterpiece of biological engineering, a compact package in which molecular order and cellular design are woven together to protect and nourish a future plant. For scientists trying to understand how crops such as the yellow pea…...
Collagen Switch Turns Fish Fins Into Limb-Like Structures
15+ hour, 8+ min ago (83+ words) When the first fish lineage crawled onto land some 375 million years ago, its fins had to be remodeled into limbs capable of bearing weight. Evolutionary biologists have long focused on the genes that pattern the skeleton—Hox clusters, Sonic hedgehog,…...
New Rust Toolkit Supercharges Sex Determination Studies in Non-Model
16+ hour, 18+ min ago (628+ words) A new open-source software package promises to transform how biologists hunt for the genetic switches that separate males from females in species with no reference genome....