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News
MissenseHMM annotates missense variants by jointly modeling pathogenicity
1+ week, 1+ day ago (769+ words) Every day, laboratories and clinics around the world generate genetic sequences in which a single letter of the DNA code has been swapped for another, and many of these changes alter the amino acid composition of the proteins those genes…...
EasyGrid Simplifies Cryo-Electron Microscopy Sample Preparation | Microbiology
3+ week, 31+ min ago (421+ words) EasyGrid Simplifies Cryo-Electron Microscopy Sample Preparation Labroots EasyGrid Simplifies Cryo-Electron Microscopy Sample Preparation A new method published in Nature Methods removes much of the guesswork and time-consuming optimization from sample preparation for cryo-electron microscopy and tomography (cryo-EM/ET). To image…...
Viral Enzyme Disables Bacterial Defenses for Phages
3+ week, 5+ day ago (485+ words) Scientists have found how phages, viruses that infect bacteria, orchestrate an explosion of protein modifications inside host cells that helps them evade the bacteria's immune systems As antimicrobial resistance grows around the world, novel therapies to counter it become increasingly…...