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News
New AI Pipeline Turns Tangled 3D Brain Videos into Clear Neuronal Activity
1+ day, 11+ hour ago (529+ words) Neuroscientists can now record electrical storms of activity from tens of thousands of neurons at once, but a stubborn bottleneck has long stood between the raw data and discovery: turning enormous three-dimensional calcium imaging videos into clean, trustworthy lists of…...
How mitochondria adapt with age: mechanisms, resilience, and therapies
3+ day, 11+ hour ago (744+ words) Mitochondria have long been cast as the batteries of the cell, and their decline has been framed for decades as the molecular equivalent of a battery running flat: less ATP, more reactive oxygen species, and faster ageing. A new review…...
3D-printed chip vascularizes kidney organoids derived from human stem cells
1+ week, 1+ day ago (81+ words) Kidney organoids grown from human stem cells have transformed how researchers study kidney development and disease, but they have always shared one stubborn flaw: they lack blood vessels. Now a team at Maastricht University in the Netherlands has unveiled a…...
An extraordinary exploration of the extracellular environment
1+ week, 2+ day ago (768+ words) Editorial from Development’s latest Special Issue - The Extracellular Environment in Development, Regeneration and Stem Cells, edited by Alex Hughes and Rashmi Priya. The post An extraordinary exploration of the extracellular environment appeared first on the Node. [Editorial from Development’s latest…...
Engineered genomic attachment sites for site-specific recombinases enable high-efficiency integration in plants and human cells | Nature Biotechnology
1+ week, 5+ day ago (710+ words) Nature Biotechnology (2026) Cite this article The luciferase activity was measured using a Dual-Luciferase Reporter Assay System (Promega) according to the manufacturer’s protocol. All assays were performed in white 96-well plates (Sangon Biotech, 400 µl, high adsorption) with a SuperMax 3000AL luminometer (Flash…...
Lee Jang-cheol joins Catholic University to lead genomics and precision medicine
1+ week, 6+ day ago (13+ words) CHOSUNBIZ Chosunbiz...
[Science Through Covers] AI rivals human experts in RNA pseudoknot folding challenge
2+ week, 1+ day ago (485+ words) Stanford and Carnegie Mellon’s Eterna platform uses AI-designed pseudoknot secondary structures to build novel 3D RNA architectures This week’s cover of the international journal 'Science' features the 'pseudoknots' of several ribonucleic acids (RNA). A pseudoknot is a structure in which a…...
News: UNCOVERseq Exposes Off-Targets Missed by Established Standards
2+ week, 5+ day ago (379+ words) An new end-to-end nomination workflow improves the nomination of genomic sites that may be unintentionally edited by CRISPR-Cas, combining high analytical sensitivity with a comparatively manageable list of candidates for confirmation. Tests in cell lines and human HSPCs suggest clinical…...