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News
Can Mammoths Return? Scientists Launch Unexpected Plan
2+ week, 8+ hour ago (172+ words) Could the legendary giant of the Ice Age — the woolly mammoth — reappear in the future? The US-based company Colossal Biosciences is studying the DNA of ancient mammoths and working to combine their key traits with the modern elephant genome. The…...
Single-cell RNA sequencing maps gonadal changes during sex reversal in
2+ week, 4+ day ago (606+ words) A single-cell transcriptomic study of the orange-spotted grouper, Epinephelus coioides, is offering an unprecedented view of how a fish gonad reorganizes itself during hormone-induced sex reversal. The research focuses on a remarkable biological system: this species is a protogynous hermaphrodite,…...
Scientists identify crucial steps that initiate DNA replication
3+ week, 5+ day ago (599+ words) Scientists have uncovered a molecular sequence that helps cells decide when to begin copying their DNA, revealing how a dormant replication machine is converted into an active engine for genome duplication....
Environmental Stress May Have Loosened DNA Repair Rules on the Y Chromosome
23+ hour, 8+ min ago (795+ words) A provocative new hypothesis published in the open-access journal Epigenetics Communications proposes that prolonged environmental stress in the ancient southern Levant may have transiently loosened the normally rigid rules of DNA repair in one specific human Y-chromosome lineage, allowing rare…...
Transfer Learning Reconstructs the Signaling Histories of Single Cells
17+ hour, 17+ min ago (704+ words) Every cell in the body carries a hidden biography. Long before a researcher harvests a tissue and sequences its contents, that cell has been bombarded by hormones, growth factors, cytokines and stress signals, and its current state is the accumulated…...
USA scientist awarded NIH grant to advance DNA repair research
3+ week, 4+ day ago (441+ words) A researcher from the University of South Alabama has received a $156,000 National Institutes of Health (NIH) grant to develop new tools for studying proteins that play a critical role in repairing damaged DNA. Aishwarya Prakash, Ph.D., professor of biochemistry and…...
Scientists Created Females and Restarted Sexual Reproduction using a Single Male Mouse
2+ week, 5+ day ago (596+ words) that decades-old cell samples can ultimately feed lost diversity back into a breeding program....
KAIST develops technology reversing irreversible biological changes,
3+ week, 1+ day ago (534+ words) A cell that has become cancerous, aged or otherwise abnormal may appear to have crossed a biological point of no return. Once its internal molecular circuitry has stabilized in a new state, removing the original trigger often does not restore…...
Single-cell study reveals sex-specific nonlinear trajectories of immune
3+ week, 1+ day ago (614+ words) A new study published in Nature Communications is drawing attention to an increasingly important question in immunology: does the immune system age in the same way in women and men? The research, led by H. Park, N. Le Bert and A. Bertoletti, examines…...
Viral Enzyme Disables Bacterial Defenses for Phages
3+ week, 4+ day ago (485+ words) Scientists have found how phages, viruses that infect bacteria, orchestrate an explosion of protein modifications inside host cells that helps them evade the bacteria's immune systems As antimicrobial resistance grows around the world, novel therapies to counter it become increasingly…...