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Lee Jang-cheol joins Catholic University to lead genomics and precision medicine
1+ week, 5+ day ago (13+ words) CHOSUNBIZ Chosunbiz...
Microscopic lab worms take center stage in Wormlympics
3+ week, 2+ day ago (207+ words) In the end, Geraldine Seydoux's molecular biology and genetics lab at the School of Medicine takes the...
News: UNCOVERseq Exposes Off-Targets Missed by Established Standards
2+ week, 5+ day ago (379+ words) Tests in cell lines and human HSPCs suggest clinical value for guide selection and preclinical risk assessment...is senior manager of bioinformatics applications development at IDT and the study's corresponding author...Volume alone proves nothing, so the authors built a…...
Whole-Body Proteome Atlas Reveals 41 Potential Cancer Drug Targets
3+ week, 2+ hour ago (575+ words) Anatomical subregions and fetal tissues were left unmapped, and direct comparisons between healthy tissues...the human proteome is essential for a deeper understanding of human biology and disease,” said the authors...Tissue-specific expression of protein drug targets might contribute to…...
Stowers Institute partners with Google DeepMind and leading research institutions to help reveal the regulatory language of the human genome
5+ day, 8+ hour ago (750+ words) Researchers provided biological expertise and feedback that helped guide the development of a new AI-powered...Stowers Institute Bioinformatics Scientist and Zeitlinger Lab member, Melanie Weilert, served as a lead...author on the AlphaGenome project....
EasyGrid Simplifies Cryo-Electron Microscopy Sample Preparation | Microbiology
2+ week, 6+ day ago (421+ words) EasyGrid, automates sample vitrification and grid optimization, reducing the cost and time required to conduct...The study authors showed that by employing jet vitrification, EasyGrid enabled the acquisition of cryoEM...
Multi-modal data integration uncovers predictive biomarkers for ovarian
1+ week, 3+ day ago (742+ words) Yet the promise has repeatedly stumbled in clinical trials, where aberration-guided therapies have too...
Engineered genomic attachment sites for site-specific recombinases enable high-efficiency integration in plants and human cells | Nature Biotechnology
1+ week, 4+ day ago (710+ words) Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed...Directed evolution of hyperactive integrases for site specific insertion of transgenes....Rapid in silico directed evolution by a protein language model with EVOLVEpro....
How genes and sex jointly shape cognition in Philadelphia youth cohort
1+ week, 2+ day ago (876+ words) One of the largest genetic investigations of cognition ever conducted in young people has found that...
Scientists uncover tRNA changes driving Chagas parasite transformation
3+ week, 2+ day ago (308+ words) Throughout its life cycle, the parasite takes on different forms....Janaina de Freitas Nascimento, Professor at the Institute of Chemistry at USP and co-author of the study...