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News: UNCOVERseq Exposes Off-Targets Missed by Established Standards
2+ week, 4+ day ago (379+ words) An new end-to-end nomination workflow improves the nomination of genomic sites that may be unintentionally edited by CRISPR-Cas, combining high analytical sensitivity with a comparatively manageable list of candidates for confirmation. Tests in cell lines and human HSPCs suggest clinical…...
Springer Nature Honors Standout Journal Editors With 2026 Editor of
17+ hour, 45+ min ago (636+ words) Springer Nature has opened the nomination window for its 2026 Editor of Distinction Awards, the annual program through which the publishing house recognizes the editors and editorial boards whose behind-the-scenes judgment shapes the scientific record....
Springer Nature Honors Standout Editors With 2026 Awards
4+ hour, 8+ min ago (662+ words) Springer Nature has opened the nomination and selection process for its Editor of Distinction Awards 2026, an annual program designed to recognize the editors whose behind-the-scenes judgment keeps the scientific record trustworthy....
Prime Editing Gets a Size Upgrade: Researchers Insert Large DNA Fragments
14+ hour, 2+ min ago (653+ words) The gene-editing field has long faced a stubborn trade-off. Tools such as CRISPR-Cas9 excel at cutting DNA and at making small, targeted changes, but installing large pieces of genetic material into a genome at a precise location — without causing collateral…...
Stowers Institute partners with Google DeepMind and leading research institutions to help reveal the regulatory language of the human genome
4+ day, 8+ hour ago (750+ words) AI-powered resource released today. For the first time, scientists can explore a comprehensive map of more...
Brain mega-enhancers compartmentalize transcriptionally active long genes
2+ week, 5+ day ago (55+ words) A previously unrecognized layer of genome organization has been identified in the mammalian brain, where exceptionally long genes and the enormous enhancers that regulate them assemble into a distinct nuclear territory. The discovery, reported in Nature Cell Biology, suggests that…...
Night Shift: Scientists Decode Clubroot Gene Activity After Dark
1+ week, 6+ day ago (130+ words) The Parasite That Works the Night Shift: Clubroot Disease Rewires Crop Plants After Dark Every night, as sunlight fades and photosynthesis grinds to a halt, plants quietly reconfigure their metabolic machinery, shifting resources toward growth, repair, and defense. New research…...
Meet Dubai teen who earned UAE's second Biology Olympiad medal without practical training
4+ week, 1+ hour ago (1545+ words) accounting for half of the IBO assessment, Yu said the news initially left him questioning whether a medal was...
[Science Through Covers] AI rivals human experts in RNA pseudoknot folding challenge
2+ week, 11+ hour ago (485+ words) findings in 'Science' on the 27th (local time) showing that AI-designed pseudoknot secondary structures...
Scientists identify crucial steps that initiate DNA replication
3+ week, 5+ day ago (599+ words) Scientists have uncovered a molecular sequence that helps cells decide when to begin copying their DNA, revealing how a dormant replication machine is converted into an active engine for genome duplication....