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News: UNCOVERseq Exposes Off-Targets Missed by Established Standards
2+ week, 5+ day ago (379+ words) He is senior manager of bioinformatics applications development at IDT and the study's corresponding...author....Volume alone proves nothing, so the authors built a benchmarking dataset in which nominated sites were...But when the authors summed the full off-target burden…...
Whole-Body Proteome Atlas Reveals 41 Potential Cancer Drug Targets
3+ week, 5+ hour ago (575+ words) the human proteome is essential for a deeper understanding of human biology and disease,” said the authors...Tissue-specific expression of protein drug targets might contribute to off-target effects, leading the authors...targets, including 41 tumor-enriched proteins with potentially minimal off-target toxicity,…...
Transient histone deacetylase inhibition reveals cell type invariant and specific effects of chromatin decondensation on irradiation response
2+ week, 5+ hour ago (362+ words) The authors would like to thank all the members of RMcC lab for their fruitful suggestions in developing...The authors would like to acknowledge the University of Tennessee Advanced Microscopy and Imaging Center...Behind each article we publish stands a…...
EasyGrid Simplifies Cryo-Electron Microscopy Sample Preparation | Microbiology
2+ week, 6+ day ago (421+ words) The study authors showed that by employing jet vitrification, EasyGrid enabled the acquisition of cryoEM...
Engineered Viruses Light Up Bacteria in Minutes by Releasing Reporter
1+ day, 9+ hour ago (707+ words) days, and the fastest molecular tests demand expensive laboratory infrastructure and highly trained staff...
Stowers Institute partners with Google DeepMind and leading research institutions to help reveal the regulatory language of the human genome
5+ day, 12+ hour ago (750+ words) Stowers Institute Bioinformatics Scientist and Zeitlinger Lab member, Melanie Weilert, served as a lead author...
Archaea as "flexitarians": ammonia-oxidizing microbes also feed on amino acids
1+ week, 2+ day ago (193+ words) Excellence 'Microbiomes drive planetary health'" says Michael Wagner, head of the FWF-Cluster and last author...
Cellular Life Process Captured Live for First Time
3+ week, 3+ day ago (221+ words) Biology and director of the Huck Center for Structural Biology at Penn State and co-corresponding author...
Scientists uncover tRNA changes driving Chagas parasite transformation
3+ week, 2+ day ago (308+ words) Janaina de Freitas Nascimento, Professor at the Institute of Chemistry at USP and co-author of the study...
Viral Enzyme Disables Bacterial Defenses for Phages
3+ week, 4+ day ago (485+ words) of exciting developments, the CRISPR-Cas9 gene-editing system among them," said Mikhail Savitski, Senior...added Nassos Typas, Senior Scientist and Head of Molecular Systems Biology Unit at EMBL....