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News
News: UNCOVERseq Exposes Off-Targets Missed by Established Standards
2+ week, 4+ day ago (379+ words) An new end-to-end nomination workflow improves the nomination of genomic sites that may be unintentionally edited by CRISPR-Cas, combining high analytical sensitivity with a comparatively manageable list of candidates for confirmation. Tests in cell lines and human HSPCs suggest clinical…...
BenchHub Turns Computational Biology Benchmarking Into a Living,
11+ hour, 17+ min ago (618+ words) Every day, computational biologists release new methods for analyzing genomes, single cells, microbiomes and molecular signatures, and every day researchers struggle with the same question: which method actually works best for their data? The answer usually depends on benchmarks—structured…...
Mitogenomics Reveals Matrilineal Evolution of Southeast Asia’s Mahseer
2+ week, 22+ hour ago (1087+ words) Decoding Sumatra’s “King of the River”: First Complete Mitogenome of the Enigmatic Mahseer Traces an Ancient Maternal Line Through Sunken Worlds Deep in the fast-flowing headwaters of northern Sumatra glides a fish that local communities have revered for generations as…...
Moving turtle nests to save the eggs can have hidden consequences
2+ week, 4+ day ago (21+ words) Phys.org This site can’t be reached phys.org refused to connect....
Scientists Discover CD55 Is the Hidden Switch That Powers Natural Killer
16+ hour, 45+ min ago (680+ words) Natural killer cells have long been celebrated as the swift, unsung assassins of the immune system, capable of detecting and destroying tumor cells without the elaborate priming that T cells require....
Night Shift: Scientists Decode Clubroot Gene Activity After Dark
2+ week, 6+ hour ago (130+ words) The Parasite That Works the Night Shift: Clubroot Disease Rewires Crop Plants After Dark Every night, as sunlight fades and photosynthesis grinds to a halt, plants quietly reconfigure their metabolic machinery, shifting resources toward growth, repair, and defense. New research…...
NJU-PKU Team Achieves High-Fidelity Lensless Imaging of Dynamic Scenes in
2+ week, 6+ day ago (562+ words) Lensless cameras may soon become far more capable of recording moving biological samples, thanks to a new computational imaging framework developed by researchers at Nanjing University and Peking University in China....
Genome sequencing reveals chromosomal fusion behind early XY sex chromosome
1+ week, 23+ hour ago (86+ words) In a discovery that offers one of the clearest snapshots yet of sex chromosomes caught in the act of being born, researchers in China have mapped the earliest stages of X and Y chromosome evolution in the darkbarbel catfish (Tachysurus…...
KAIST develops technology reversing irreversible biological changes,
3+ week, 1+ day ago (534+ words) A cell that has become cancerous, aged or otherwise abnormal may appear to have crossed a biological point of no return. Once its internal molecular circuitry has stabilized in a new state, removing the original trigger often does not restore…...
Single-cell RNA sequencing maps gonadal changes during sex reversal in
2+ week, 4+ day ago (606+ words) A single-cell transcriptomic study of the orange-spotted grouper, Epinephelus coioides, is offering an unprecedented view of how a fish gonad reorganizes itself during hormone-induced sex reversal. The research focuses on a remarkable biological system: this species is a protogynous hermaphrodite,…...