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News
Prime Editing Gets a Size Upgrade: Researchers Insert Large DNA Fragments
19+ hour, 35+ min ago (653+ words) The gene-editing field has long faced a stubborn trade-off. Tools such as CRISPR-Cas9 excel at cutting DNA and at making small, targeted changes, but installing large pieces of genetic material into a genome at a precise location — without causing collateral…...
Optical strain and spectral-spatial networks decode micro-expressions
1+ week, 1+ day ago (61+ words) Micro-expressions are the fleeting, involuntary facial movements that betray a person’s true emotional state in a fraction of a second, often lasting less than half a second and appearing on the face before any conscious attempt at suppression can take…...
Field nanopore sequencing yields non-lethal genome assembly of endangered
2+ week, 10+ hour ago (831+ words) Scientists Sequence the Full Genome of a Critically Endangered Caribbean Frog Without Killing It — Entirely on the Island It Calls Home In the mist-draped rainforests of Grenada, researchers have quietly achieved something that until recently would have demanded a killing…...
New study explains how RNA droplets may have helped start life
3+ week, 2+ day ago (552+ words) BUFFALO, N.Y. — Before the first cells enclosed chemistry inside membranes, life faced a basic logistical problem: molecules needed to find one another in a hostile, watery environment. RNA may have offered an answer....
Plant RNA Switching Reveals Heat-Tolerance Transcripts Controlled by SIZ1
2+ week, 1+ day ago (65+ words) As rising temperatures threaten plant growth and agricultural productivity, researchers have identified a molecular editing process that helps Arabidopsis seedlings respond to heat. The study, published in Stress Biology, shows that the SUMO E3 ligase SIZ1 influences which ending individual messenger RNA…...
Barley Cold-Inducible Disordered Protein CISP Acts as a Small RNA Chaperone
2+ week, 2+ day ago (55+ words) Cold-Induced Barley Protein Helps Plants Keep RNA Unwound in the Deep Cold Subject of Research: The role of the cold-induced barley protein CISP as an RNA chaperone and mediator of cold tolerance Subject of Research: Agriculture Article Title: CISP, an…...
New Sequencing Method Maps RNA Isoforms Across Brain Cells With Single-Cell
7+ hour, 51+ min ago (529+ words) Every cell in the brain carries essentially the same genome, yet the same gene can produce a startling variety of RNA molecules. Through a process called alternative splicing, segments of a gene’s transcript can be included, skipped, or rearranged, generating…...
Stowers Institute partners with Google DeepMind and leading research institutions to help reveal the regulatory language of the human genome
4+ day, 13+ hour ago (750+ words) Researchers provided biological expertise and feedback that helped guide the development of a new AI-powered resource released today. For the first time, scientists can explore a comprehensive map of more than 9 billion possible single-letter DNA changes Credit: Stowers Institute for…...
Genome-Wide Study Reveals lncRNAs and miRNAs Regulating Radish Flower
6+ day, 4+ hour ago (833+ words) Development Bioengineer.org...
WGS2IBI: Cloud Workflow Enables Personalized Bayesian Analysis of Genome
1+ week, 20+ min ago (747+ words) A team of computational geneticists and epidemiologists has unveiled a cloud-based workflow that promises to strip away one of the most persistent barriers in precision medicine: the sheer difficulty of analyzing whole-genome sequencing data at scale, reproducibly, and without access…...