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News
Hierarchical AI model unifies single-cell multiomics data through deep
4+ day, 5+ hour ago (829+ words) artificial intelligence framework that promises to make sense of one of the most data-rich but technically...
NicheTrans Enables Spatially Aware Translation Across Omics Data
2+ week, 6+ day ago (526+ words) more complete view of how cells behave inside tissues, but that promise has often come with a steep technical...
Transient histone deacetylase inhibition reveals cell type invariant and specific effects of chromatin decondensation on irradiation response
2+ week, 7+ hour ago (362+ words) Tennessee Advanced Microscopy and Imaging Center (RRID:SCR_028273) for instrument use and scientific and technical...
New R package Geneslator simplifies gene ID conversion and annotation
1+ week, 3+ day ago (715+ words) Every high-throughput sequencing experiment ends in the same place: a very long list of genes, each tagged with an identifier that may be meaningless outside the specific database from which it was pulled....
New tool Dory analyzes differences in image-based chromatin tracing data
1+ week, 3+ day ago (690+ words) Researchers at the University of Virginia and Yale School of Medicine have introduced a new computational method designed to detect structural differences in the three-dimensional organization of the genome between groups of cells, addressing one of the most pressing analytical…...
Transfer Learning Reconstructs the Signaling Histories of Single Cells
1+ day, 18+ hour ago (704+ words) Every cell in the body carries a hidden biography. Long before a researcher harvests a tissue and sequences its contents, that cell has been bombarded by hormones, growth factors, cytokines and stress signals, and its current state is the accumulated…...
Stowers Institute partners with Google DeepMind and leading research institutions to help reveal the regulatory language of the human genome
5+ day, 14+ hour ago (750+ words) Researchers provided biological expertise and feedback that helped guide the development of a new AI-powered resource released today. For the first time, scientists can explore a comprehensive map of more than 9 billion possible single-letter DNA changes Credit: Stowers Institute for…...
Scientists Develop Real-Time Control Systems for Engineered Biology
3+ week, 6+ day ago (510+ words) Engineered living cells are becoming miniature biological factories, capable of producing medicines, sustainable chemicals and other valuable products. They can also be designed to sense disease-related signals or respond to changing conditions inside the human body. Yet unlike machines built…...
East German Plant Genetics Pioneer Thomas Börner Celebrates 80th Birthday
2+ week, 5+ day ago (684+ words) A scientist who conducted molecular genetics research behind the Iron Curtain, built international collaborations before German reunification, and helped reveal how chloroplasts communicate with the cell nucleus is being celebrated as one of Germany’s pioneering plant geneticists. Professor Thomas Börner,…...
AI Translates Light Microscopy Into Electron-Microscope Detail to Speed
1+ day, 10+ hour ago (534+ words) Mapping the wiring of the brain at nanometer resolution has long demanded a punishing trade-off: electron microscopy can reveal every synaptic cleft and organelle, but imaging even a cubic millimeter of neural tissue this way takes months or years of…...