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News
Transfer Learning Reconstructs the Signaling Histories of Single Cells
1+ day, 18+ hour ago (704+ words) Every cell in the body carries a hidden biography. Long before a researcher harvests a tissue and sequences its contents, that cell has been bombarded by hormones, growth factors, cytokines and stress signals, and its current state is the accumulated…...
Male Mice Cloned into Both Sexes, Reproduce
3+ week, 5+ day ago (350+ words) mouse’s blood cells and inserted them into enucleated eggs—a method known as somatic cell nuclear transfer...Somatic cell nuclear transfer has already been applied in various mammals beyond mice....
Transient histone deacetylase inhibition reveals cell type invariant and specific effects of chromatin decondensation on irradiation response
2+ week, 7+ hour ago (362+ words) After irradiation, cells were transferred back to an incubator and kept at 37 °C with 5% CO2....
Rare homozygous TTPA variant linked to ataxia with vitamin E deficiency
5+ day, 8+ hour ago (699+ words) In a striking reminder of how much can hide inside two neighboring letters of the genetic code, researchers in Iran have identified a rare complex mutation in the TTPA gene that causes ataxia with vitamin E deficiency, a treatable but…...
A genomic catalog of Earth’s bacterial and archaeal symbionts
2+ day, 13+ hour ago (918+ words) The assembly of a genomic catalog devoted specifically to bacterial and archaeal symbionts represents a meaningful shift in how large-scale microbiome resources are organized....
Scientists Created Females and Restarted Sexual Reproduction using a Single Male Mouse
2+ week, 6+ day ago (596+ words) They created fertile female mice from cells carrying the male genome. How many parents does it take to make a family? According to a new study, just one. In a striking experiment, researchers in Japan used cells from male mice…...
Hybrid nanofluid blood flow modeled in ciliated porous concentric tubes
1+ week, 3+ day ago (754+ words) Cilia are tiny, whip-like filaments that line many of the body’s internal passages, and when they beat in coordinated waves they can push fluid along without any external pump....
Mitogenomics Reveals Matrilineal Evolution of Southeast Asia’s Mahseer
2+ week, 1+ day ago (1087+ words) Decoding Sumatra’s “King of the River”: First Complete Mitogenome of the Enigmatic Mahseer Traces an Ancient Maternal Line Through Sunken Worlds Deep in the fast-flowing headwaters of northern Sumatra glides a fish that local communities have revered for generations as…...
Jumping Plant Lice Genome Study Rewrites the Family Tree of Triozidae
1+ day, 9+ hour ago (587+ words) A team of researchers in China has sequenced the first complete mitochondrial genome of the jumping plant louse Bactericera gobica and, by combining it with nearly every other Triozidae mitogenome available, assembled the most comprehensive genetic dataset ever compiled for…...
Scientists Create Polycaprolactone-Based 2D Platelets Through Living
2+ week, 6+ day ago (593+ words) A new polymer-assembly protocol is turning a familiar biodegradable polyester into precisely shaped two-dimensional nanomaterials. In a study published in Nature Protocols, Xia, Xiao, Yadav and colleagues describe how to prepare ultrathin poly(ε-caprolactone), or PCL, platelets whose lateral dimensions…...