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News
Damaged lysosomes undergo budding-type fission driven by mitochondrial
1+ week, 3+ day ago (59+ words) The process, termed budding-type fission, or B-fission, allows a compromised lysosome to bud off small...
Transient histone deacetylase inhibition reveals cell type invariant and specific effects of chromatin
2+ week, 1+ hour ago (362+ words) Young L, Pal D, Davern S and McCord RP (2026) Transient histone deacetylase inhibition reveals cell type...
News: UNCOVERseq Exposes Off-Targets Missed by Established Standards
2+ week, 5+ day ago (379+ words) An new end-to-end nomination workflow improves the nomination of genomic sites that may be unintentionally edited by CRISPR-Cas, combining high analytical sensitivity with a comparatively manageable list of candidates for confirmation. Tests in cell lines and human HSPCs suggest clinical…...
Stowers Institute partners with Google DeepMind and leading research institutions to help reveal the regulatory language of the human genome
5+ day, 8+ hour ago (750+ words) “This is a very difficult problem because every cell type speaks a slightly different language, making...“With AlphaGenome, we can quickly query many cell types and look for general patterns by which genes...
Multiancestry GWAS and multiomics reveal cellular origins of multiple
6+ day, 14+ hour ago (855+ words) across multiple ancestries with cutting-edge multiomics analyses to reveal where, and in which cell types...
Whole-Body Proteome Atlas Reveals 41 Potential Cancer Drug Targets
3+ week, 1+ hour ago (575+ words) By plotting the cellular routes across 25 cancer types, the team revealed how the proteome changes during...Early mass spectrometry efforts provided better precision, but covered only ~30 healthy tissue types....The team identified 1,717 tissue-enriched proteins across 74 tissue types; 480 of these proteins…...
Meet Dubai teen who earned UAE's second Biology Olympiad medal without practical training
4+ week, 1+ day ago (1545+ words) With practical examinations accounting for half of the IBO assessment, Yu said the news initially left...One required him to dissect and classify five types of flies, a particularly uncomfortable prospect for...
Mass General Brigham Uses Pig Kidney Bridge to Human Transplant in Landmark Case
1+ week, 1+ day ago (481+ words) Tim Andrews, a 66-year-old American man, had end-stage renal failure caused by type 2 diabetes and was...The team used the kidney of a “Yucatan mini pig,” a type of small pig breed, and performed gene editing...
Hierarchical AI model unifies single-cell multiomics data through deep
3+ day, 23+ hour ago (829+ words) working with a collaborator at the University of California, Irvine, have unveiled a new artificial intelligence...
AI Helps Researchers Decode DNA Sequence Crucial for Gene Activation
3+ week, 2+ day ago (614+ words) whether a human gene is turned on or remains silent has been decoded with the help of artificial intelligence...