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Industry focus e Book: Genomics (4th edition)

7+ hour, 20+ min ago  (333+ words) Advances in genomics and molecular biology are transforming how researchers study disease, gene regulation, and cellular function across healthcare and life science applications. In our latest Genomics Editorial e Book, we've compiled expert insights, emerging research, and application-focused articles that…...

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New 3 D immunohistochemistry method enhances deep tissue imaging

11+ mon, 2+ week ago  (177+ words) "POD-n Abs, camelid n Abs fused with POD, enhanced immunolabeling depth and enabled sensitive detections by combining with our original fluorescent tyramide signal amplification system, FT-GO," said Dr. Yamauchi. "Quenching of POD activity with Na N3 allowed for multiplex immunolabeling of…...

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Breakthrough research uncovers multiple autism subtypes with unique traits

10+ mon, 3+ week ago  (424+ words) Researchers at Princeton University and the Simons Foundation have identified four clinically and biologically distinct subtypes of autism, marking a transformative step in understanding the condition's genetic underpinnings and potential for personalized care. This approach enabled the discovery of clinically…...

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Broken String Biosciences rebrands to reflect strategic evolution as demand grows for unbiased genome-wide off-target analysis

2+ mon, 5+ day ago  (922+ words) Broken String Biosciences, a biotechnology company enabling gene editing teams to accelerate development of safer, more effective genetic medicines, today introduced new branding and comprehensive website as part of its strategic repositioning. Broken String Biosciences rebrands to reflect strategic evolution…...

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Expanded Seq-Scope method boosts gene-mapping resolution within tissues

3+ mon, 5+ day ago  (391+ words) In 2021, a technology developed at University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity within intact tissue at microscopic resolution, enabling researchers to measure all expressed m RNA molecules and determine precisely where they are located within…...

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Two main methods for discovering disease genes reveal distinct aspects of biology

6+ mon, 4+ week ago  (325+ words) The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While both methods are widely used, the research found that they identify different genes, with major implications for drug development. Publishing online Nov....

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Galectin-3 found to drive crucial cell fusion in early placental development

6+ mon, 4+ week ago  (448+ words) Now, scientists at Scripps Research have identified a key player in the placenta's transformation-a molecule called galectin-3 that binds to sugar molecules on specific cell surface proteins, likely holding placental cells tightly together to fuse. The research, published in Proceedings…...

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CZI and NVIDIA collaborate to accelerate life science research through virtual cell models

7+ mon, 1+ week ago  (701+ words) Today, the Chan Zuckerberg Initiative (CZI) and NVIDIA announced an expanded collaboration to accelerate life science research by driving development and adoption of virtual cell models through tools, data, models, and benchmarks delivered through CZI's virtual cells platform (VCP). CZI…...

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Rare spacecraft bacterium found to evade detection by playing dead

7+ mon, 3+ week ago  (528+ words) A rare microorganism found in an unexpected environment may be evading detection by "playing dead," according to microbiologists at the University of Houston. Discovered in NASA spacecraft assembly clean rooms, this rare novel bacterium, called Tersicoccus phoenicis (T. phoenicis), could have…...

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A direct-to-biology approach to streamline PROTAC synthesis and profiling

7+ mon, 4+ week ago  (610+ words) Figure 1. Overview of the automated D2 B platform developed at Charnwood allowing high-throughput PROTAC hit finding and rapid SAR generation. Image Credit: Concept Life Sciences" D2 B is a semi-automated process that allows fast biological assessment of crude reaction mixtures within a…...