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The ultimate guide to understanding protein–protein interactions in biology

11+ hour, 56+ min ago  (863+ words) Understanding PPIs is critical for advancing research in cell biology and medication development. PPIs are characterized according to stability, longevity, and the types of proteins involved. Protein-protein interactions are classified in numerous ways: They can be classified as obligatory (in…...

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Two main methods for discovering disease genes reveal distinct aspects of biology

3+ mon, 1+ week ago  (325+ words) The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While both methods are widely used, the research found that they identify different genes, with major implications for drug development. Publishing online Nov....

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Galectin-3 found to drive crucial cell fusion in early placental development

3+ mon, 1+ week ago  (448+ words) Now, scientists at Scripps Research have identified a key player in the placenta's transformation-a molecule called galectin-3 that binds to sugar molecules on specific cell surface proteins, likely holding placental cells tightly together to fuse. The research, published in Proceedings…...

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CZI and NVIDIA collaborate to accelerate life science research through virtual cell models

3+ mon, 3+ week ago  (701+ words) Today, the Chan Zuckerberg Initiative (CZI) and NVIDIA announced an expanded collaboration to accelerate life science research by driving development and adoption of virtual cell models through tools, data, models, and benchmarks delivered through CZI's virtual cells platform (VCP). CZI…...

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Rare spacecraft bacterium found to evade detection by playing dead

4+ mon, 1+ week ago  (528+ words) A rare microorganism found in an unexpected environment may be evading detection by "playing dead," according to microbiologists at the University of Houston. Discovered in NASA spacecraft assembly clean rooms, this rare novel bacterium, called Tersicoccus phoenicis (T. phoenicis), could have…...

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A direct-to-biology approach to streamline PROTAC synthesis and profiling

4+ mon, 1+ week ago  (610+ words) Figure 1. Overview of the automated D2B platform developed at Charnwood allowing high-throughput PROTAC hit finding and rapid SAR generation. Image Credit: Concept Life Sciences" D2B is a semi-automated process that allows fast biological assessment of crude reaction mixtures within a plate, shortening…...

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Synthetic Biology and the Pursuit of Living Diagnostics

7+ mon, 1+ week ago  (1746+ words) In this interview, Professor James J.Collins, co-founder of the field of Synthetic Biology, discusses his journey to founding the field of synthetic biology and the potential of next-generation diagnostics and living therapeutics. I come from a technical family. My mom…...

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The future of molecular microbiology begins now

7+ mon, 3+ week ago  (471+ words) Driven by the fundamental human desire to understand the world around us, the biological sciences began as a quest to uncover how life works. But the landscape began to shift with the rise of sequencing technologies. What was once slow…...

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New technology unlocks cellular ancestry with DNA barcodes

7+ mon, 3+ week ago  (729+ words) A landmark study by WEHI scientists has shed new light on one of the most fundamental mysteries of biology: how cells divide and grow into the complex structures that make up our bodies. The study has produced a sophisticated and…...

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Utah State biologist investigates chromosomal changes driving evolution

8+ mon, 11+ hour ago  (299+ words) How do living things evolve? What is the myriad of processes by which generic variations in a population affect organisms' survival and allow reproduction in an ever-changing environment? Why do these processes often crawl over millennia and yet, sometimes, rapid…...