10+ hour, 23+ min ago  (673+ words) Distinguishing between bipolar disorder and schizophrenia is often difficult since the two conditions share many biological traits. A team at King's College London identified separate genetic pathways for each, finding that markers unique to schizophrenia drive cognitive decline while shared…...

2+ week, 3+ hour ago  (512+ words) In large-scale proteomics, the volume of data generated makes manual validation of every spectrum impossible. Consequently, the field has adopted the target-decoy approach to estimate and control the false discovery rate (FDR) (Table 1). This involves searching the MS/MS spectra…...

3+ mon, 1+ week ago  (1198+ words) Astrocytes are a type of cell that's found in the brain," Foster explained. They're very widely dispersed in all different kinds of mammals, certainly invertebrates, and they perform a lot of different functions. We call them astrocytes as a collective,…...

11+ mon, 2+ day ago  (568+ words) One of the key challenges of the modern genomics era is studying the thousands of genes in a single human cell at scale. To overcome this, scientists have developed PERISCOPE, which combines the power of microscopy imaging with CRISPR screening....