Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a promising new strategy to make cancer-fighting immune cells stronger and potentially longer-lasting, a discovery that could help improve the effectiveness of immunotherapies that use a patient's own immune…
Experts at the 2025 ICE-T Symposium reviewed CAR T-cell therapy, bispecific antibodies, and gene therapy across myeloma, lymphoma, autoimmune disease, and solid tumors, emphasizing safety and access. The analysis included 128 patients treated with BCMA-directed CAR T-cell therapy between December 2019 and December…
This eBook brings together perspectives from across the AAV development and manufacturing continuum. It explores how early commercial planning can help avoid costly delays, how standardized platform approaches and off-the-shelf plasmids can streamline development, and how next-generation innovations are helping…
A Blood Research review describes the spectrum of alloimmune hemolytic anemia after ABO-incompatible stem cell transplantation and proposes host- and graft-associated classifications. Immune-mediated alloimmunization and hemolytic anemia can complicate ABO-incompatible hematopoietic stem cell transplantation, and a new review in Blood…
Restoring the peroxisomal fission protein PEX11β improved motor and cognitive deficits and mitochondrial gene expression in a toxin-induced mouse model of Huntington's-like disease, with Yin Yang 1 identified as a key regulator of PEX11β and Complex II co-expression. In a study published in…
Researchers generated the first two CRISPR chd2-knockout zebrafish strains and found that a four-base deletion and a one-base deletion in the same gene produced opposite effects on embryo mortality, deformity and larval excitability. Article Title: Effects of two chd2-knockout strains…
IXICO PLC (LSE:IXI, OTC:PHYOF, FRA:PYPB), the brain imaging analytics company, has presented research suggesting that reducing differences between MRI scanners does not always make it easier to track Huntington's disease. The work was shown at the European…
A tiny implant provides a groundbreaking treatment for macular telangiectasia A new surgical implant tested in Boston is giving hope to patients with macular telangiectasia, or MacTel, a rare eye disease that impairs central vision and makes it difficult to…
An IV hydration business that sold stem cell and exosome infusions alongside its wellness drips has been told by the FDA that those products are unapproved drugs. The agency posted the warning letter to Calibrate IV Hydration on Oct. 27, two…
UC San Francisco scientists engineered B-SYNC CAR-T cells that activate only in the brain and cleared diffuse midline glioma in mouse models, with human trials planned as early as April 2027.
Living medicines: engineered immune cells, gene therapies delivered by viral vectors, and treatments made from stem cells, with their trials and approvals.
An article joins this feed when it matches these terms. Each one is also a search of its own.