Immune cells, pictured here in bright teal, occupy the epithelial layers between the skin surface and its stem cells and act as a system regulator. (Credit: Fuchs lab) "Essentially, Langerhans cells act as liaisons to regulate host-microbe interactions, while joining…
Decidual macrophages (dMÏ) contribute to maternalâfetal tolerance. However, the mechanism of dMÏ differentiation during pregnancy is still largely unknown. Here, we report that receptor activator for nuclear factor-κB ligand (RANKL), secreted by... Uncover the latest and most impactful research…
Simon Conway working in his lab. Newswise — Scientists at the Indiana University School of Medicine have gained new insights into Barth syndrome, a rare genetic disorder that primarily affects males. In this study, researchers found that the mouse models had…
Licensable perturbation dataset to include transcriptomes and proteomic secretomes for understanding the human immune response. Parse Biosciences, the leading provider of scalabl... Parse Biosciences and Nomic Announce 100 Million Cell, Multimodal AI-ready Dataset for Immune Biology 29 Oct 2026 - 13:00 Licensable perturbation dataset to…
A cross-sectional study of 100 Algerian dromedary camels reports that dehydration is associated with a thinner splenic marginal zone and reduced B-cell density. Dehydration thins the spleen's immune hub in desert camels Subject of Research: Dehydration-associated remodeling of the splenic marginal…
A systematic comparison of nine CNN architectures on label-free multimodal microscopy images of colonic tissue found ResNet50 with partial fine-tuning and augmentation delivered the best balance of accuracy, stability and parameter efficiency in a 20-patient IBD study. Artificial intelligence models trained…
A randomized, sham-controlled trial in 24 healthy adults found that transcutaneous auricular vagus nerve stimulation primed platelets and accelerated clotting kinetics on thromboelastography, while combined vagal and trigeminal stimulation primed platelets through a different pathway without altering clotting kinetics. Article Title:…
A toxic union for neurons Given these results, the researchers designed an innovative strategy to trick the Poly-GR dipeptides and reduce their toxicity. They created a trap, a molecule that mimicked the specific rRNA sequence to which Poly-GR dipeptides bin…
Corresponding author Yongqiang Feng, PhD, St. Jude Department of Immunology. “We found that under normal conditions, the COMPASS pathway enables regulatory T cells to prevent inflammation and autoimmunity in the intestine,” said corresponding author Yongqiang Feng, PhD, St. Jude Department…
A microscopic image of an intestinal organoid in which the nuclei of the cells are blue, epithelial cells are white, T cells are green and other immune cells are red.Antonio Santos Autoimmune Conditions July 24, 2024 Balls of intestinal cells from…
How the immune system defends the body and how it goes wrong: immune cells and antibodies, autoimmune disease and inflammation, and the science of vaccines.
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