WEST LAFAYETTE — Researchers at Purdue University and the National Heart, Lung, and Blood Institute have uncovered an unexpected role for a human immune protein that could help scientists better understand how the body responds to infections, including HIV. The study,…
[Life] The RNA World theory was proposed as a way to explain the origin of the DNA-RNA-Protein relationship found all current cells. It has been greatly strengthened by experimental work on ribozymes and non-enzymatic replication, and has become the most…
For the past two years, Dr. Jesse Bloom, Professor in Fred Hutch’s Basic Sciences and Public Health Sciences Divisions, and postdoctoral fellow Dr. Tyler Starr have engaged in a high-stakes race... The evolving landscape of sarbecovirus ACE2 binding For the past…
Shotgun metagenomics sequences DNA collected from an entire community rather than from a single isolated organism. In soil, that means mixing genetic fragments from bacteria, fungi, plants, and other life forms. Researchers then need to determine where those fragments came…
During Japan’s rainy season and again in autumn, mushrooms often sprout on park lawns and sports fields. Scientists who study mushrooms, though, have paid far more attention to the fungi of forests. When researchers surveyed lawns in Japan, they found…
We thought that if a user points their phone at a leaf and the app returns “Monstera deliciosa” with 99% accuracy, the job was done. We were completely wrong. After months of real-world testing with thousands of gardeners, students, and plant…
A combined microbiome and cultivation study shows tomato plants selectively recruit stress-adapted rhizobacteria under salinity and drought, yielding 127 isolates with in vitro plant growth-promoting traits.
Whole-genome sequencing of 23 clinical isolates from China shows that 16S rRNA sequencing misidentifies Nocardia gipuzkoensis as N. abscessus, with highest susceptibility to trimethoprim–sulfamethoxazole, linezolid, and amikacin. The team examined 23 strains of N. gipuzkoensis isolated from clinical cases in China between 2017 and…
Researchers built a human blood-brain barrier model combined with antiviral testing, validated it with anti-HIV drugs, showed TBEV crosses an intact barrier to infect astrocytes, and identified a barrier-permeable antiviral candidate. Subject of Research: An in vitro human blood-brain barrier…
A comprehensive review shows that fungal glutamate dehydrogenases act as integrative regulators of nitrogen metabolism, morphogenesis and infection, with inhibitors of these enzymes showing antifungal potential.
The microbial world: bacteria and archaea, viruses and phages, the microbiomes living in and on us, drug-resistant superbugs and fungi.
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