Saponins are tensioactive secondary metabolites produced by plants, valued in the pharmaceutical and food industries for their emulsifying and stabilizing properties. Quantifying them, however, has long been an analytical headache: these molecules lack chromophores in their structure, which restricts their…
Training for new users consists of: Once the training is complete, researchers may schedule their experiments through the director of Mass Spectrometry (Stephen Eyles) or online through CORUM at corum.umass.edu. CORUM - the centralized ordering system for shared facilities.
Andrei Fedorov and his team have found a way to take some of the guesswork out of mass spectrometry imaging (MSI), potentially giving scientists better tools to explore the molecules that influence our health. A small sample of human tissue…
A statistical SERS strategy turned intensity-distribution shapes into concentration fingerprints, enabling a neural network to classify five rhodamine 6G levels with 100% accuracy in laboratory tests.
/PRNewswire/ -- Metabolon, Inc., the global leader in metabolomics solutions advancing life sciences research, diagnostics, therapeutics, and precision... New bioinformatics application combines curated metabolite-protein knowledge, advanced network algorithms, interactive exploration, and optional AI interpretation to generate clearer mechanistic hypotheses MORRISVILLE, N.C., Oct.
An integrative analysis of more than 2,300 human phosphoproteomics datasets identifies serines 168, 169 and 189 as the predominant phosphorylation sites on PANK2 and maps extensive co-phosphoregulatory networks connecting the enzyme to PI3K-AKT, MAPK, autophagy and energy-sensing signaling. News Source: Diana Fleming. (October 26, 2026). Massive Phosphoproteomics…
Mass photometry (MP) is a cutting-edge technique that allows for the precise measurement of the mass of single molecules in solution. MP offers valuable insights into the molecular weight and oligomeric states of biological macromolecules and complexes. Other ways to…
Gary Siuzdak explains how uMRM converts inconsistent untargeted LC–MS data into standardized MRM transitions. In this ASMS interview, Gary Siuzdak from the Scripps Research Institute discusses untargeted multiple reaction monitoring (uMRM), which offers a broad, systematic framework for connecting untargeted…
ASMS 2026 highlights a potential paradigm shift in metabolomics, as new evidence suggests many unknown signals are ESI artifacts. Metabolomics has emerged as one of the most powerful tools for understanding biological systems because metabolites represent the downstream products of gene…
Proteins are the engines of living systems. Which proteins are made, where, and in what amounts can provide important information about the health of systems, clues as to what happens in the case of disease, and potential approaches to fighting…
Measuring proteins and metabolites at scale: mass-spectrometry proteomics, protein sequencing, affinity panels and metabolomics platforms.
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