Whether you are part of our community or are interested in joining us, we welcome you to WashU Medicine. Study redefines picobirnaviruses as only the third known group of bacteria-infecting RNA viruses by Marta Wegorzewska•October 29, 2026 WashU Medicine researchers have…
A combination of advanced methods Materials provided by University of Konstanz. Note: Content may be edited for style and length. This Alien Planet Should Have Lost Its Atmosphere Billions of Years Ago A Routine Blood Test Could Predict Dementia Risk…
Researchers have developed an efficient algorithm that partitions the RNA branching parameter space to reveal all distinct optimal secondary structures a sequence can adopt. News Source: Gregory Coleman. (October 29, 2026). New Algorithm Maps Every Optimal RNA Fold Across Branching Parameters. Scienmag.
CaMKII is involved in long-term potentiation, the enhanced signaling between neurons that underlies memory formation (reviewed in Lisman et al., 2002). Researchers know that upon neural stimulation, CaMKII arrives at the post-synapse within seconds (Shen and Meyer, 1999) and proteasomal proteins follow…
BET inhibition suppresses STING expression at its promoter and enhancer regions, weakening the immune response triggered by PARP inhibitors. Bromodomain-containing protein 4 (BRD4), a central member of the bromodomain and extra-terminal (BET) protein family that drives tumor progression, has been identified as…
Osteoarthritis (OA) is a chronic joint disease and hard to cure at present. Accumulating evidence suggests long noncoding RNA-HOTAIR (lncRNA-HOTAIR) plays important role in OA progression. However, the underlying molecular mechanism of HOTAIR in OA... Thank you for visiting nature.
A new review synthesizes a decade of evidence showing that long noncoding RNAs regulate insulin resistance, beta-cell failure and diabetic complications, with circulating transcripts reaching diagnostic accuracy near 0.84 AUC.
The team behind the new work confirmed that circMAP2K4 has a stable, circular topology and resides predominantly in the cytoplasm, the cellular compartment where such molecules can act as molecular sponges that bind and sequester other regulatory RNAs. The findings extended…
Are you sure you want to import this news into? Single-molecule detection of chromatin interaction dynamics of PRC2 (labeled in green) on chromatin fibers (labeled in red, t=0) (credit: Beat Fierze/EPFL) Scientists at EPFL and Max Plank have made significant…
Researchers report this month that MALAT1, a long non-coding RNA that is implicated in certain cancers, regulates pre-mRNA splicing -- a critical step in the earliest stage of protein production. Their study appears in the journal Molecular Cell. Nearly 5 percent of the…
RNA's many jobs in the cell: noncoding RNA, microRNA, RNA splicing and modifications, ribosomes and how proteins are translated.
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