Licensable perturbation dataset to include transcriptomes and proteomic secretomes for understanding the human immune response. Parse Biosciences, the leading provider of scalabl... Parse Biosciences and Nomic Announce 100 Million Cell, Multimodal AI-ready Dataset for Immune Biology 29 Oct 2026 - 13:00 Licensable perturbation dataset to…
A systematic comparison of nine CNN architectures on label-free multimodal microscopy images of colonic tissue found ResNet50 with partial fine-tuning and augmentation delivered the best balance of accuracy, stability and parameter efficiency in a 20-patient IBD study. Artificial intelligence models trained…
A four-patient PET study found that the activated T cell tracer [18F]F-AraG is best quantified with a two-tissue irreversible model and a tumor-to-plasma ratio, with no treatment-induced kinetic changes during STING agonist and anti-PD-1 immunotherapy. Subject of Research: Pharmacokinetic modeling…
A toxic union for neurons Given these results, the researchers designed an innovative strategy to trick the Poly-GR dipeptides and reduce their toxicity. They created a trap, a molecule that mimicked the specific rRNA sequence to which Poly-GR dipeptides bin…
Corresponding author Yongqiang Feng, PhD, St. Jude Department of Immunology. “We found that under normal conditions, the COMPASS pathway enables regulatory T cells to prevent inflammation and autoimmunity in the intestine,” said corresponding author Yongqiang Feng, PhD, St. Jude Department…
A microscopic image of an intestinal organoid in which the nuclei of the cells are blue, epithelial cells are white, T cells are green and other immune cells are red.Antonio Santos Autoimmune Conditions July 24, 2024 Balls of intestinal cells from…
"'How could this work?' we asked ourselves," said Caspi. "Scientists are like little kids, when they get an answer to one question, there is immediately the next level of 'why?' So we started looking at the deeper mechanisms that make…
Trillions of bacteria live in the human gut without triggering an immune response. Scientists at St. Jude Children's Research Hospital have now discovered a gene-regulatory pathway that helps maintain this delicate balance. COMPASS pathway helps regulatory T cells prevent intestinal…
An open-access study combined label-free brightfield microscopy, machine learning, and SHAP-based explainability to classify 17,781 red blood cells across ten morphology classes with an F1 score of 0.89.
Yale School of Medicine initiates a new research initiative in the field of inflammation science, thanks to a generous gift. Newswise — Yale School of Medicine (YSM) was awarded a $10 million grant from the Blavatnik Family Foundation (BFF) to launch a…
When immunity attacks the body: the biology of lupus, multiple sclerosis, type 1 diabetes, rheumatoid arthritis and chronic inflammation, and research on resetting the immune system.
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