A new review maps how extracellular vesicles mediate liver-cardiovascular crosstalk, finding the strongest evidence for liver-to-vascular signaling and calling for standardized methods. Liver disease and cardiovascular disease are linked through metabolic, immune, hemodynamic, and vascular pathways, and a new review…
Our study shows, for the first time, an optically acquired 3D image of dendritic spines in human brain tissues. These had not been possible due to the lack of compatible labeling and tissue-clearing... BioTechniques is part of Taylor & Francis Group. Taylor…
Lingyan Shi is currently a tenured Associate Professor in the Shu Chien-Gene Lay Department of Bioengineering at UC San Diego. She arrived at UC San Diego in 2019, following her postdoctoral training... Host: Dr. Tulio Valdez Multimodal Nanoscopy for Visualizing Metabolic…
Researchers have generated and validated a goat-derived gamma-tubulin antibody that labels basal bodies under methanol fixation and enables multiplex staining alongside rabbit- and mouse-derived antibodies. Article Title: A goat-derived gamma-tubulin antibody for triple-channel imaging of primary cilia News Source: Drew…
Researchers developed a cellulose, carbon nanotube, and silver nanowire composite tape that supports wrinkle-free, charging-free serial SEM imaging of brain sections without glow discharge or carbon coating.
A new rat study shows that an image-derived input function with population-based metabolite correction can quantify the synaptic vesicle tracer [18F]SynVesT-1 non-invasively, closely tracking arterial blood-based measurements.
Medical solutions provider STEMart has launched a range of gel imaging system solutions to support molecular biology research, electrophoresis analysis and laboratory documentation. A gel imaging system usually comprises a UV transmission lamp, a hood or darkroom to shield against…
Researchers have introduced Bioloc3D, an open-source ImageJ and Python toolset that automates three-dimensional quantification of fluorescent elements and their colocalizations across entire microscopy stacks. Subject of Research: An open-source toolset for automated 3D quantification of fluorescent labeling and colocalization in microscopy Article…
"By providing a tool that can observe neuronal activity in real time, our technology could be used to study the pathology of diseases at the earliest stages," said Yunyang Li, the first author of the paper. "This could help researchers…
An open-access study combined label-free brightfield microscopy, machine learning, and SHAP-based explainability to classify 17,781 red blood cells across ten morphology classes with an F1 score of 0.89.
Light microscopy advances: super-resolution and expansion microscopy, light-sheet and live-cell imaging, and fluorescent probes.
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